PerkinElmer Announces New Collaboration with the National Center for Drug Screening to Advanced Personalized Medicine and Drug Profiling in China

21 Apr 2014
Sarah Thomas
Associate Editor

Product news

PerkinElmer, Inc., a global leader focused on improving the health and safety of people and the environment, today announced a new collaboration with the National Center for Drug Screening (NCDS) to advance personalized medicine and drug profiling in China. Through sharing knowledge, expertise and innovative capabilities, the two organizations will establish a personalized drug research and development platform that will validate biomarkers for individualized disease treatment for Chinese patients.

Special guests including key governmental leaders, Mr. Jianjun Cheng, CCP Secretary of Shanghai Institute of Materia Medica, Chinese Academy of Sciences; Mr. Weihua Song, Deputy Director of Shanghai Zhangjiang INNOPARK Administrative Committee; Mr. Robert Friel, PerkinElmer's Chairman and Chief Executive Officer; and Dr. Ming-Wei Wang, Director of NCDS among others, participated in a ceremony today celebrating the collaboration at the Chinese National Compound Library in Zhangjiang Hi-tech Park, Shanghai.

"It is an honor for PerkinElmer to collaborate with Dr. Wang, who is one of the pioneers in the field of personalized medicine," Mr. Friel said. "We look forward to working with Dr. Wang, the National Center for Drug Screening and Chinese scientists to develop a significant personalized drug research and development technology platform which will enable patients to be treated more accurately, safely, and efficiently."

The program will include sequencing patient samples in order to establish genomic information for drug profiling, including validation of biomarkers for personalized disease treatment and related informatics solutions. As a part of this program, PerkinElmer and NCDS will first undertake a study on metabolic diseases to validate new diagnostics for the Chinese populations through utilizing next generation sequencing technologies. Once optimized, the technology platform will be implemented in testing laboratories and hospitals throughout China.

"As an important customer and long-term collaborator of PerkinElmer in the field of life sciences and drug discovery, the National Center for Drug Screening is committed to the research and development of new and effective drugs," Dr. Ming-Wei Wang said, "For the majority of drugs that are available in China, the respective biomarkers have not yet been fully validated. We are very excited to build this state-of-the-art personalized medicine program with PerkinElmer which will allow us to offer vital insights to improve the quality of healthcare in China."

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Genome AnalysisGenomics, the study of genomes, includes functional genomics, evolutionary genomics and comparative genomics. There are many genomic technologies such as DNA sequencing of whole genomes, computational biology and bioinformatics. DNA and nucleic acids must be isolated and concentrated from cells for analysis with kits, automated analyzers and software. Other useful technologies for studying genomics include PCR, microarrays and electrophoresis.BiomarkersBiomarkers are biological markers which can be measured and evaluated to indicate a biological state. The use of biomarkers in research and diagnosis can indicate a normal or disease state or drug response of cells / tissues. Biomarkers include genetic markers, cell surface markers such as antigens, antibodies or receptors and secreted molecules such as cytokines. An assay system is required for identification of biomarkers. :Biopharmaceutical AdvancesBiopharmaceutical advances follow the development of pharmaceuticals derived from biotechnology, also known as biotechnology medicines. Biopharmaceuticals may be produced from cell lines, plants, or microbial cells. Important considerations of biopharmaceutical use include application, cost, production process and purification.Clinical GeneticsMolecular Genetics covers the analysis of hereditary genetic disease and chromosomal abnormalities. Genetics can be analysed using DNA, RNA, and protein microarrays, PCR, RT PCR and DNA sequencing. Genetic equipment includes genetic workstations, thermal cyclers, cooling blocks and electrophoresis products. Diagnostic kits are used for DNA / RNA extraction and purification.TherapeuticsTherapeutics are treatments designed to alleviate or cure diseases. These include pharmaceuticals, biologics, and gene therapies, which work by targeting specific disease mechanisms. Advances in personalized medicine and biologics offer new hope for patients with conditions that were previously difficult to treat. Browse our peer-reviewed product directory to find therapeutic solutions for various diseases; compare products, check user reviews, and get pricing directly from manufacturers.Drug DevelopmentDrug development refers to the process of bringing a new drug to market.Precision MedicinePrecision medicine refers to the idea of customized healthcare, where medical decisions and treatments are tailored to the individual patient. Molecular diagnostics, companion diagnostics and Next Generation Sequencing (NGS) play a pivotal role in this approach. Drug Discovery & Development ScreeningBiomarker DiscoveryClinical biomarkers refer to substances related to known medical conditions that can be accurately measured <i>in vitro</i>. Biomarkers can be used to diagnose presence of a disease and indicate disease severity. The discovery of new biomarkers is incredibly valuable in the field of diagnostics.