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Penn State College of Medicine, Penn State Milton S. Hershey Medical Center Selects Research Informatics Solutions from GenoLogics

GenoLogics
19 Apr 2007

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GenoLogics, a leading developer of lab and data management software solutions for life sciences research, today announced that Penn State College of Medicine and Penn State Hershey Medical Center have selected Geneus™ and Proteus™ to manage their research informatics needs across multiple labs and multiple science domains. Both solutions will be installed in multiple core labs within the college and the medical center, and will be instrumental in enabling operational and scientific research excellence.

Proteus and Geneus are robust lab and data management solutions, each purposed for a specific scientific discipline, and they are built on GenoLogics’ configurable lab informatics platform, OMIX, that acts as the ‘central nervous system’ across multiple labs.

“It was crucial for us to choose a solution we can implement quickly across multiple labs, with immediate benefits for our researchers and bioinformaticians. These systems will assist us in becoming an NCI-designated Cancer Center, while enabling our longer term bioinformatics and translational medicine visions,” stated Richard Rauscher, Director of Information Technology for Penn State Cancer Institute.

Penn State Hershey Medical Center will use Geneus and Proteus to manage sample data and workflows in a number of core labs including: functional genomics, molecular genetics, macromolecular, proteomics/mass spectrometry, cell science/flow cytometry, transgenic, microscopy imaging, MRI/NMR, and viral vector cores.

Bruce Stanley, Director, Section of Research Resources at Penn State College of Medicine, commented, “We extensively evaluated a number of LIMS vendors, and we chose GenoLogics because their solutions are deeply purposed and configurable to address our science needs, but based on a common lab informatics platform that we can implement across multiple labs. GenoLogics was able to show us they can easily accommodate the unique needs of our labs and our informatics requirements.” Because of the open architecture and configurability of the lab informatics platform, Proteus and Geneus seamlessly integrate with a multitude of instruments and software, freeing scientists to use the best tools for their research.

Penn State Hershey is a leader in translational medicine and cancer research, with the goal of contributing to scientific knowledge, the practice of medicine, and the education of health professionals. GenoLogics’ lab informatics platform is ideally suited for enabling Penn State Hershey Medical Center’s long term translational medicine initiatives. Geneus and Proteus support information and data transfer requirements between clinical and research domains, and facilitate data integration and interchange with other supporting systems, providing an enabling platform to facilitate translational research.

Geneus and Proteus will support this vision with science-specific features including: genotyping, gene expression, and quality control modules; peptide centric-results and analysis; automated data capture; protein search results analysis; and automated bioinformatics pipelining. These solutions also provide a central repository of data that will greatly ease collaboration between labs. The overall solution for Penn State includes genomics and proteomics purposed modules, and can also be quickly and easily configured to accommodate other application areas.

Michael Ball, GenoLogics CEO, stated “I am very excited that Penn State Hershey has chosen GenoLogics – we’re confident our solutions are ideal for linking their labs, managing their data and accommodating the breadth of sciences included in their research areas. We also look forward to working with them in the future to implement our research LIMS solution as a mechanism to enable their translational research initiatives.”

Penn State Milton S. Hershey Medical Center was founded in 1963 through a gift from The Milton S. Hershey Foundation. Located in Hershey, Pa., Penn State Hershey Medical Center is a 501-bed teaching and research hospital. Its campus also includes Penn State College of Medicine (Penn State’s medical school) and Penn State Children’s Hospital—the south central Pennsylvania region’s only children’s hospital.

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Mass SpectrometryMass spectrometry (MS) is a powerful analytical technique used to identify and quantify molecules based on the mass-to-charge ratio of gas-phase ions. It provides detailed information about the structure, composition, and properties of compounds and is widely used across fields such as environmental monitoring, materials science, drug discovery and development, food and beverage testing, and wider chemical research. Key MS techniques include tandem mass spectrometry (MS/MS), liquid chromatography–mass spectrometry (LS-MS) and inductively coupled plasma (ICP-MS). Choosing from these wide range of techniques and technologies can be a daunting task, so keep up to date with scientific applications, performance expectations, and customer reviews here all in one place. Visit our product directory to receive quotes direct from the manufacturer. NMR and EPR SpectroscopyNuclear magnetic resonance (NMR) spectroscopy is used to resolve the local chemical environment of atomic nuclei with spin, revealing information on molecular structure, dynamic processes and chemical reactions of organic molecules, from proteins to synthetics. Electron paramagnetic resonance (EPR) also known as electron spin resonance (ESR) spectroscopy is used to detect and quantify paramagnetic species in a sample, including free radicals as transition metal ions. By immersing the sample in a strong magnetic field, both NMR and EPR spectrometers probe the sample with either radio waves or microwaves respectively. A range of benchtop, solid-state and time domain NMR spectrometers & EPR spectrometers are available, as well as NMR tubes, NMR solvents, software, coils, and magnets. Find the best NMR & EPR equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Genome AnalysisGenomics, the study of genomes, includes functional genomics, evolutionary genomics and comparative genomics. There are many genomic technologies such as DNA sequencing of whole genomes, computational biology and bioinformatics. DNA and nucleic acids must be isolated and concentrated from cells for analysis with kits, automated analyzers and software. Other useful technologies for studying genomics include PCR, microarrays and electrophoresis.ProteomicsProteomics is the systemic bioinformatics study of proteins and amino acids, including their structure, size, function and identification. Tools used in proteomics include chromatography, blotting and gels, protein arrays, mass spectrometry and ELISA and associated analysis software. Analyzers and proteomic systems should be sensitive, high resolution, fast and may be automated for high-throughput.LIMSLIMS (Laboratory Information Management System) is an informatics software system used to improve the quality assurance and quality control (QA / QC) of data management. LIMS can be a standard for common lab workflows, such as commercial off the shelf systems (COTS), or customized for more specialized lab use. Systems are available for mainframe computers or PC.Chem / BioinformaticsCheminformatics and bioinformatics are computational techniques used in chemistry and biology, respectively, for data acquisition, processing and storage. Cheminformatics focuses on compound information, whereas bioinformatics is mainly applied to analysis and modeling of genomics, genetic and sequencing information. Hardware and software is available for data acquisition, analysis, management and storage.Flow Cytometry / Cell CountingFlow cytometers are used to count, sort and examine multiple characteristics of cells. Other cell analysis equipment includes image cytometers, cell counters, fluorescence-activated cell sorters (FACS), magnetic-activated cell sorters (MACS), and a range of flow cytometry assay kits. Flow cytometers can reveal information on cell viability, cell proliferation, apoptosis and cell cycle progression, as well as identify cell populations and intracellular or cell-surface molecules. Additionally, some flow cytometers, known as FACS, have an additional sorting function after analysis. Cell counters and image cytometers count live and dead cell populations and can also conduct cell proliferation assays. Find the best flow cytometers, cell counters and cell sorters in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Light MicroscopyLight microscopes or optical microscopes are used to visualize microscale objects under magnification, including cells, clinical specimens and materials. Lab equipment for light microscopy includes confocal microscopes, fluorescence microscopes, zoom and stereo microscopes. Microscope slides and imaging reagents are available for visualizing samples, as well as various microscope stages and incubators for large or temperature-sensitive samples. Find the best light microscopes in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.

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Penn State College of Medicine, Penn State Milton S. Hershey Medical Center Selects Research Informatics Solutions from GenoLogics