Partnership to explore ion mobility technology in glycoscience

MOBILion Systems, Inc. is partnering with Dr. Lance Wells and Dr. Michael Tiemeyer, principal investigators at the Complex Carbohydrate Research Center, University of Georgia, for evaluation of its patented ion mobility separations technology, called Structures for Lossless Ion Manipulation (SLIM), for the research of glycans and glycoproteins. The SLIM platform will address existing challenges in glycobiology and help researchers better understand the correlation between glycan structure and function.

MOBILion’s technology advances the capabilities of current liquid chromatography-mass spectrometry (LC-MS) analytical workflows, enabling multi-dimensional analysis of biologically relevant molecules with high levels of resolution and throughput. By extending the ion mobility path far beyond other devices, the technology produces more extensive separations to reveal previously undetectable molecules. The SLIM technology can be integrated with LC-MS workflows to provide more robust analytical information, and for some applications, replace liquid chromatography by providing speed, ease-of-use, and resolution. MOBILion enables the high-resolution separation and analysis of glycans, glycoproteins and glycopeptides.

“MOBILion is excited to partner with experts in glycomics, glycoproteomics, and glycobiology at the Complex Carbohydrate Research Center,” said Melissa Sherman, Chief Executive Officer. “The CCRC is a leading institution that works with academics, clinical researchers, and pharmaceutical companies to teach the world glycan analysis for applications in biomarker discovery, biotherapeutic characterization and clinical sample analysis. The collaboration between MOBILion’s SLIM technology and Drs. Wells and Tiemeyer has the potential to shift the paradigm in glycobiology research with enhanced resolution, isomer separation and high-throughput analysis.”

Dr. Wells stated, “Based on exciting preliminary findings, we are eager to partner with MOBILion to solve some of the leading analytical challenges facing the biologics and glycobiology community.” According to Dr. Tiemeyer “SLIM technology holds great promise for revolutionizing glycoanalytics and achieving new depth in understanding glycan structure and function.”

MOBILion’s beta product will be released to key collaborators in 2020 with broader commercial availability planned for 2021.

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