Pall Laboratory: Clear Choice, Clear Options in Filtration

Pall Life Sciences - Laboratory, Food, Beverage

11 Jan 2016

Lynsey Forsyth

Post Doc / Research Fellow

Product news

Visit Pall Laboratory at the SLAS 2016 conference in San Diego, CA and talk with product specialists to learn more about Filtration, Separation and Purification product and applications.

Pall Laboratory provides the most complete offering of high throughput filter plates to meet the sample prep needs across a wide range of research applications. The AcroPrep™ Advance filter plates are available in both 96-well and 384-well formats for applications including lysate clearance, DNA binding, multiplexing, DNA and Protein detection and more.

Pall has maintained a leadership position through continuous innovation across a wide product portfolio. Within the molecular product offering, Pall recently introduced the 1K Macrosep® and Microsep™ Advance centrifugal devices, extending the wide range of molecular weight cut-off options. The 1K centrifugal devices reliably concentrate, separate and desalt nucleic acids and protein samples with recoveries above 90%.

These Pall products help support automation of the filtration process, so that it can be completed in-batch or in-process via automation, strengthening researcher’s ability to accelerate sample processing, and maximize sample recovery

Stop by our booth # 1244

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AcroPrep™ Advance Filter Plates for Lysate Clearance
Pall Life Sciences - Laboratory, Food, Beverage
The AcroPrep™ Advance filter plates for lysate clearance effectively remove cellular debris quickly and allow for the use of additional wash steps to maximize sample recovery. Filtration can be accomplished by either vacuum manifold or centrifugation, ultimately maximizing your choice in protocols. The purification of biomolecules (DNA, RNA and proteins) from prokaryotic and eukaryotic cell lines can be problematic. The AcroPrep™ Advance filters plates for lysate clearance provide a prefilter for relatively quick and easy clarification of samples: in addition, the new well geometry ensures faster flow rates and reduced hold up volumes for efficient recovery of biomolecules.Features: Integrated prefilter yields consistent filtration of samples with high levels of gross particulate New well geometry results in faster, more uniform filtration rates across the plate with reduced hold-up volume Manufactured with biologically inert materials that allow clarification of most types of lysates without loss of the target molecule Applications: Removal of Bacterial debris prior to plasmid purification Removal of bacterial and cellular debris prior to protein purification Clearance of gross particulates
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AcroPrep™ Advance Filter Plates for Ultrafiltration
Pall Life Sciences - Laboratory, Food, Beverage
AcroPrep™ Advance Filter Plates for Ultrafiltration Provides rapid, efficient separation of biomolecules. Omega™ membrane provides high recovery and typically results in > 90% recovery of target biomolecules. New well design results in faster, more uniform filtration rates across the plate with reduced hold-up volume for maximum sample recovery Intrinsic plate and membrane properties prevent target molecules from binding to the plate. Application: Size exclusion, PCR clean-up, Nucleic acid purification, Protein separation.
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AcroPrep™ Advance Filter Plates for Protein Purification
Pall Life Sciences - Laboratory, Food, Beverage
AcroPrep™ Advance Filter Plates- Advancing sample preparation Features of the AcroPrep™ Advance Filter Plates: • Smooth well design – Provides consistency in filtration times, as well as efficient sample and bead recovery. • Optimized outlet tips – Minimizes sample leakage during incubation steps and reduces the presence of hanging drops following filtration. • New well geometry – Results in faster , more uniform filtration rates across the plate, thereby improving well-to-well, plate-to-plate, and lot-to-lot consistency. • 100% visual inspection – Ensures each well has proper membrane placement and is free from debris. • Automation compatible – Manufactured in accordance with SBS guidelines, allowing plates to be run in manual, semi-automated, and automated processes. Applications of the AcroPrep™ Advance Filter Plates: • Lysate clearance • DNA purification • Protein purification • Multiplexing assays • Bead-based assays • Flow cytometry • Neonatal screening • Size exclusion • Concentration, purification, and desalting of proteins and nucleic acids • Aqueous filtration • Particulate removal • Solvent filtration
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AcroPrep™ Advance 96-Well Filter Plates for DNA Purification
Pall Life Sciences - Laboratory, Food, Beverage
Maximum Yields of High Quality DNA. Optimized for maximum binding yield of DNA from a variety of sample types New well geometry results in reduced hold-up volume and higher recovery of DNA New outlet tip geometry provides direct flow of samples into receiver plate without concerns of crosscontamination Enhanced membrane ensures high yields of contaminant-free DNA for downstream applications Manufactured in accordance with SBS guidelines, allowing entire DNA purification process to be performed on automated equipment
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AcroPrep™ Advance 96-Well Filter Plates for Multiplexing
Pall Life Sciences - Laboratory, Food, Beverage
Superior Bead Recovery and Low Levels of False Positives Ensure Assay Reproducibility. Smooth well wall provides efficient bead recovery, ensuring reproducible results lot after lot High performance membrane does not trap microspheres in the membrane matrix In serological assays, Supor® membrane effectively removes IgG complexes, thus reducing nonspecific reactivity of the microspheres and reducing false positives New well design results in faster, more uniform filtration rates across the plate with reduced hold-up volume New outlet tip geometry minimizes sample leakage and loss during incubation steps so that acquisition times are not affected Intrinsic plate and membrane properties minimize target loss from non-specific binding
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AcroPrep™ Advance 96-Well Filter Plates for Solvent Filtration
Pall Life Sciences - Laboratory, Food, Beverage
Robust Chemical Resistance Provides Compatibility with Harsh Organics. Chemically resistant materials provide a stable platform to process samples in organic solvents Inert materials of construction ensure complete recovery of samples and low non-specific binding New well design results in faster, more uniform filtration rates across the plate and reduces hold-up volume Innovative outlet tip geometry provides direct flow of samples into receiver plate without concerns of cross-contamination
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Microsep™ / Macrosep® Advance Centrifugal Devices
Pall Life Sciences - Laboratory, Food, Beverage
Pall centrifugal devices simplify common nucleic acid and protein handling procedures, replacing traditional separation techniques such as column chromatography, preparative electrophoresis, dialysis, gradient centrifugation, and more. Available in various membrane types to meet your application needs.
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Macrosep® Advance Centrifugal Devices
Pall Life Sciences - Laboratory, Food, Beverage
Quickly concentrate up to 20 mL of biological sample Pall Life Sciences Macrosep Advance Centrifugal Devices Features of the Microsep Advance Centrifugal Devices: • Rapidly concentrates 20 mL sample volumes to 0.5 mL. • Provides high recoveries, typically > 90%. • Low protein-binding Omega membrane and polypropylene housing minimize losses due to non-specific binding. • Versatile Omega membrane is available in a variety of MWCOs. • Built-in deadstop prevents spinning to dryness. • Color-coded for easy identificationApplications of the Microsep Advance Centrifugal Devices: Ultrafiltration • Concentrate and desalt proteins. • Exchange buffer or remove salt of chromatography eluates and gradient fractions. • Recover proteins or other molecules from cell culture supernatants. Microfiltration • Remove particulate from aqueous solutions and clinical samples.
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AcroPrep™ Advance Filter Plates
Pall Life Sciences - Laboratory, Food, Beverage
AcroPrep™ Advance filter plates are the newest edition to Pall’s filter plate family. New sealing technology and advanced tip design make these the first choice in critical sample prep applications. Aplications: Lysate Clearance DNA purification Protein purification Multiplex assays Aqueous filtration Particulate removal Size exclusion Bead-based assays Neonatal screening Flow cytometry Solvent filtration Concentration, purification and desalting of proteins and nucleic acids Features: Smooth well design – Provides consistency in filtration times, as well as efficient sample and bead recovery Optimized outlet tips – Minimizes sample leakage during incubation steps and reduces the presence of hanging drops following filtration New well geometry – Results in faster, more uniform filtration rates across the plate, thereby improving well-to-well, plate-to-plate and lot-to-lot consistency 100% visual inspection – Ensures each well has proper membrane placement and is free from debris Automation compatible – Manufactured in accordance with SBS guidelines, allowing plates to be run in manual, semi-automated and automated processes
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