Pall ForteBio Launches the Octet® K2 System, Increasing Access to Sensitive Binding Interactions Analysis

5 Aug 2015
Chelsie Phillips
Temporary Editorial Assistant

Product news

Pall ForteBio LLC, a leading supplier of instrumentation for accelerated drug discovery and development, today announced the launch of the Octet K2® system, a new entry point into the Octet line of label-free interaction analysis systems. Now available globally, the Octet K2 system offers high-performance, budget-friendly kinetic characterization of antibody, protein and small-molecule binding interactions.

Using Pall ForteBio’s Bio-Layer Interferometry (BLI) technology, all Octet systems offer a fluidics-free alternative to surface plasmon resonance with a variety of off-the-shelf Dip and Read™ biosensors for more rapid assay development and optimization. The Octet K2 system increases accessibility to BLI as a two-channel instrument, providing exquisite binding affinity data for molecules down to 150 daltons in size.

“Label-free users in academia and at startup biotech companies have historically been stuck between choosing to pay a premium for capacity they will never use or to settle for a lower-performance ‘starter’ system,” commented Robert Wicke, General Manager at Pall ForteBio. “The Octet K2 system offers scientists throughput to meet their budget without compromising assay sensitivity.”

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BiosensorsBiosensors are devices used to detect an analyte using biological molecules specific to the analyte coupled to a detector. Biosensor instruments may be photometric, typically using surface plasma resonance (SPR), electrochemical or QCM (quartz crystal microbalance) biosensors. Biosensors should be selective, portable, robust and sensitive and have a fast response time. Systems may be manual or automated and usually have associated software.Cell-Based AssaysCell-based assays are used to monitor the presence, quantity and activities of a desired cellular analyte including drug molecules or biomarkers. This can reveal information on cell health (apoptosis, cytotoxicity, viability and proliferation assays), cell metabolism, cell migration and cell signaling mechanisms. Find the best cell-based assay products, kits and equipment with our peer reviewed product directory: compare products, check customer reviews and receiving pricing direct from manufacturers.Protein InteractionsProtein interactions are essential for understanding cellular processes, as proteins work together to carry out biological functions. Studying protein interactions can provide insights into disease mechanisms, drug development, and cell signaling pathways. Explore the best tools for protein interaction research in our peer-reviewed product directory; compare products, check reviews, and get pricing directly from manufacturers.Drug DiscoveryDrug discovery is the process of identifying potential new medications, involving stages such as target identification, compound screening, and preclinical development. It relies on cutting-edge technologies like high-throughput screening, artificial intelligence, and molecular modeling to accelerate the identification of drug candidates. Drug discovery plays a pivotal role in developing new therapies for diseases ranging from cancer to rare genetic disorders. Browse our peer-reviewed product directory to find the latest drug discovery technologies, compare options, check customer feedback, and get pricing directly from manufacturers.PharmaceuticalsPharmaceuticals are medicinal drugs used in healthcare to diagnose, prevent, cure and treat illnesses. Pharmaceuticals that are excreted after use appear in wastewater and can have detrimental effects on the environment.Label-Free AnalysisDrug DevelopmentDrug development refers to the process of bringing a new drug to market.
Pall ForteBio Launches the Octet® K2 System, Increasing Access to Sensitive Binding Interactions Analysis