Pall Corporation Expands Next Generation AcroPrep™ Advance Filter Plate Portfolio

20 Jun 2010
Sarah Sarah
Marketing / Sales

Product news

Pall Corporation has expanded its next generation 96-well filter plate portfolio to include additional membrane options and larger well volumes. These new membrane options and larger wells achieve maximize performance in diagnostic and life sciences research applications.

In addition to the plates for multiplexing and neonatal screening applications released earlier this year, the portfolio now includes plates that have been optimized for applications such as protein fractionation, lysate clarification and DNA binding.

New plates provide superior performance advantages, such as improved target recovery in nucleic acid applications and more effective processing of particulate-laden samples. The comprehensive offering of Pall’s AcroPrep Advance filter plate line addresses stringent sample preparation requirements while lowering the expenses associated with sample loss and contamination in a broad range of diagnostic and life sciences applications. Redesigned membrane sealing technology maximizes sample recovery and ensures even filtration rates well-to-well. The optimized outlet tip design reduces weeping during incubations facilitating high assay reproducibility, while the biologically inert housing of the plates ensures low non-specific binding of target analytes while maximizing sample recovery.

The combination of optimized membrane configurations and a new well design offers improved filtration rates, throughput and sample recovery. Each of these factors provides researchers with confidence that the new AcroPrep Advance plates will address many of the common problems observed with filter plate usage. In addition, the AcroPrep Advance filter plates meet SBS/ANSI guidelines allowing for easy processing in manual, semi-automated and automated modes.

AcroPrep™ Advance Filter Plates for Protein Purification

Pall Life Sciences - Laboratory, Food, Beverage

AcroPrep™ Advance Filter Plates- Advancing sample preparation Features of the AcroPrep™ Advance Filter Plates:  •  Smooth well design – Provides consistency in filtration times, as well as efficient sample and bead recovery.   •  Optimized outlet tips – Minimizes sample leakage during incubation steps and reduces the presence of hanging drops following filtration.   •  New well geometry – Results in faster , more uniform filtration rates across the plate, thereby improving well-to-well, plate-to-plate, and lot-to-lot consistency.   •  100% visual inspection – Ensures each well has proper membrane placement and is free from debris.   •  Automation compatible – Manufactured in accordance with SBS guidelines, allowing plates to be run in manual, semi-automated, and automated processes. Applications of the AcroPrep™ Advance Filter Plates:  •  Lysate clearance   •  DNA purification   •  Protein purification   •  Multiplexing assays   •  Bead-based assays   •  Flow cytometry   •  Neonatal screening   •  Size exclusion   •   Concentration, purification, and desalting of proteins and nucleic acids   •  Aqueous filtration   •  Particulate removal   •  Solvent filtration

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Sample PreparationSample preparation can improve the quality and speed of separation techniques. Products to assist sample preparation include filtration equipment, evaporators, membranes and sieves.Genome AnalysisGenomics, the study of genomes, includes functional genomics, evolutionary genomics and comparative genomics. There are many genomic technologies such as DNA sequencing of whole genomes, computational biology and bioinformatics. DNA and nucleic acids must be isolated and concentrated from cells for analysis with kits, automated analyzers and software. Other useful technologies for studying genomics include PCR, microarrays and electrophoresis.MicroplatesMicroplates are multi-well plates used to increase the throughput of biological investigations. The number of wells microplates contain can range from 6 to 3243 wells, with the 96-well format being the most commonly used. Microplates can come tailored for a range of applications including cell culture, PCR, filtration, storage, non-binding surface, protein crystallization, as well as pre-coated, deep well and normal Standard microplates. Additionally, options for microplate colors include clear , black, white or black with clear bottom and white with clear bottom for absorbance microplate reader applications. Find the best microplates for your lab in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.DNA / RNA Extraction and PurificationPurified DNA and RNA are required for numerous downstream molecular biology applications. Consequently, the importance of high-quality DNA/RNA extraction and purification equipment cannot be underestimated. Many purification kits are available and are typically optimized for nucleic acid type and source, including plasmid DNA, genomic DNA, mRNA, RNA and viral nucleic acid purification kits. Automated extraction and purification of nucleic acids can be implemented with magnetic bead separator instruments or high-throughput purification workstations. Find the best DNA/RNA extraction and purification equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.DNA SequencingDNA sequencing, such as sanger sequencing, is a biological technique that determines the precise order of nucleotide bases in a fragment or template of DNA. DNA sequencers and genetic analyzers are based on capillary electrophoresis, where labeled DNA fragments are electrophoretically separated by size as they migrate through a polymer. Find the best DNA sequencing products, including DNA sequencing kits, genomic libraries and genetic identity kits in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.