Optimized lentiviral vectors to speed up your research

AMSBIO offers a range of lentivirus production services to provide tailor-made products to support your research

25 Aug 2022
Blake Forman
Content Creator

Product news

Lentiviral vectors are a valuable tool for delivering target genes into most types of dividing and non-dividing mammalian cells in vitro and in vivo. Typically, the production of custom lentiviral vectors is a laborious and challenging process, especially when high-titer lentiviral vectors are required. The custom lentiviral vector production service from AMSBO offers researchers a proven partner to avoid this bottleneck and speed up your research.

The AMSBIO custom lentivirus service includes the design and construction of the vectors, providing you with high-quality viral particles on which you can rely. Offered for various constructs, researchers can choose from a wide range of expression vectors, depending on your desired research application.

This includes services to make ready-to-use shRNA lentivirus for your gene target and to clone your desired human cDNA ORFs into a lentiviral expression vector with options of various promoters, tags, and markers. In addition, AMSBIO offers ready-to-use anti-miRNA lentivirus for human and mouse miRNA, as well as miRNA lentivirus for any human or mouse miRNA listed in miRbase.

The latest custom lentiviral vector production services introduced by AMSBIO are Integrase-Deficient lentivirus for gene therapy research that reduces the risk of insertional mutagenesis and lentiviruses to help understand the mechanism of coronavirus (SARS-CoV-2) cell entry and how the viral tropism evolves over time.

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Genome AnalysisGenomics, the study of genomes, includes functional genomics, evolutionary genomics and comparative genomics. There are many genomic technologies such as DNA sequencing of whole genomes, computational biology and bioinformatics. DNA and nucleic acids must be isolated and concentrated from cells for analysis with kits, automated analyzers and software. Other useful technologies for studying genomics include PCR, microarrays and electrophoresis.Gene Expression and Molecular CloningMolecular cloning is a set of techniques that utilizes vectors to transfer recombinant DNA into host cells and is an essential tool for investigating the expression of genes and proteins in bacterial or mammalian cells. A variety of vectors optimized for gene cloning and expression in a range of host organisms are available, alongside competent cells for genetic replication. Here, you can explore a range of molecular tools, high-quality genomic and cDNA libraries, premade clones, transformation and transfection reagents and mutagenesis or gene expression detection assays and expression arrays. Find the best gene expression and molecular cloning products in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Protein ExpressionProtein expression is the utilization of cell machinery for the synthesis of proteins and has become a critical tool in biotherapeutic, genomic, and proteomic research. Produce recombinant proteins with expression vectors in combination with a host cell suitable for high-level protein expression. For production of toxic proteins, consider cell-free expression vectors. Create and monitor post-translational modifications with protein modification kits. Find the best protein expression products in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.VirusesViruses are microscopic pathogens that require a host cell to replicate. Understanding their structure, replication cycle, and impact on the immune system is crucial in developing effective treatments, vaccines, and diagnostic methods. Research continues to focus on emerging viral diseases and antiviral drug discovery. Explore solutions for virus research, detection, and treatment in our peer-reviewed product directory; compare products, check customer reviews, and get pricing directly from manufacturers.Gene TherapyGene therapy is a technique that modifies or replaces genes within an individual's cells to treat or prevent diseases. This approach holds potential for curing genetic disorders, cancers, and certain viral infections. Advances in gene editing technologies like CRISPR are driving the growth of gene therapy. Explore gene therapy tools and technologies in our peer-reviewed product directory; compare products, check reviews, and get pricing directly from manufacturers.miRNA