Omega Bio-tek introduces new solutions for automated endotoxin-free plasmid DNA purification

Omega Bio-tek has launched its Mag-Bind^® Endo-Free Plasmid Mini & Midi Kits. These magnetic bead-based kits are automation-friendly and designed to purify endotoxin-free (<0.1EU/μg) plasmid DNA, providing researchers with high-quality and convenient plasmid preparation solutions necessary for a wide array of applications from gene editing to molecular diagnostics.

The Mag-Bind^® Endo-Free Plasmid Midi and Mini Kits follow a modified alkaline lysis method, forming a bacterial lysate, which can then be cleared using lysate clearance beads (Mag-Bind^® Particles LC). Using beads for lysate clearance facilitates full automation of the purification process, starting from bacterial pellet.

The Kits can be automated on most open-ended liquid handlers and magnetic processors, including Omega Bio-tek's own MagBinder^® Fit24 platform. With these new Kits, researchers can now obtain endotoxin-free plasmid DNA, eliminating the need for additional centrifugation steps and saving valuable time and resources.

The Mag-Bind^® Endo-Free Plasmid Midi Kit (M1272) is optimized for purifying plasmids from up to 50 mL of bacterial culture in LB or 10 mL in TB. For smaller-scale projects, the Mag-Bind^® Endo-Free Plasmid Mini Kit (M1261) purifies plasmids from up to 1.5 mL of overnight bacterial culture in LB, TB, or other suitable growth media.

"We are thrilled to introduce our new Mag-Bind^® Endo-Free Plasmid Kits to the scientific community," says Julie Baggs, Scientific Director of Omega Bio-tek. "We understand the importance of high-quality and reliable plasmid purification for research, and these kits are designed to meet those needs. Our goal is to provide researchers with the best tools to enhance their workflows and accelerate their discoveries."

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