Omega Bio-tek announces fully automated, high-throughput endotoxin-free plasmid purification

New workflow, validated on the Dynamic Devices Lynx delivers scalable plasmid DNA extraction from Midi to Maxi-prep volumes without compromising yield or quality

7 Feb 2026

Product news

Omega Bio‑tek has announced a new automated workflow developed in collaboration with Dynamic Devices that integrates the M1272 Mag‑Bind® Endo‑free Plasmid Midi Kit into a high‑throughput, automation‑friendly platform.

This workflow is designed to meet the growing demand for scalable, endotoxin‑free plasmid purification suitable for sensitive downstream applications, including transfection, viral vector production, and gene‑editing research.

The new workflow combines Omega Bio‑tek's proven Mag‑Bind® chemistry with the advanced automation capabilities of the Dynamic Devices Lynx® platform, enabling laboratories to streamline plasmid purification while maintaining exceptional purity and reproducibility. This workflow processes up to 24 samples in ~2 hours, starting from bacterial pellet.

When initiated from resuspended pellets in Solution 1, the total runtime is reduced to ~1.5 hours. Designed to address the increasing demand for automated high‑volume plasmid purification, this workflow processes culture volumes up to 50 mL per sample and can be extended to Maxi‑prep‑scale outputs by splitting samples across plates.

By pairing this chemistry with automated liquid‑handling, the workflow minimizes hands‑on time, increases throughput, and enhances consistency across large sample batches.

As demand for high‑throughput, high‑purity plasmid purification continues to rise, this collaboration underscores Omega Bio‑tek's commitment to delivering innovative, automation‑ready solutions that support the evolving needs of molecular biology and biotechnology laboratories.

The integration of the Mag‑Bind® Endo‑free Plasmid Midi Kit into automated workflows provides researchers with a scalable, reliable, and cost‑effective approach to producing plasmid DNA suitable for the most sensitive applications.

The workflow will be showcased at the 2026 SLAS International Conference and Exhibition, where it will be featured in a Spotlight Talk presented by Tesfaye Kemsi. Attendees will have the opportunity to explore the workflow's performance data, automation benefits, and application‑specific advantages.

Omega Bio‑tek's scientific team and representatives from Dynamic Devices will be available throughout the conference to discuss implementation strategies and answer technical questions.

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Mag-Bind® Endo-free Plasmid Midi Kit

Omega Bio-Tek

Fully Automatable - Magnetic beads to clear lysate, avoiding manual centrifugation step Versatile - Process up to 50 mL bacterial cultures with different plasmid types and culture medias High-quality - Endotoxin-free plasmid DNA with endotoxin levels < 0.1 EU/µg Pure - Contamination-free plasmid DNA with A260/A280 > 1.8 and A260/A230 > 1.8

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Lynx Robotic Liquid Handling Platform

Dynamic Devices

The Lynx Robotic Liquid Handler—available in LM1800, LM1200, LM900, LM730i, and LM700 models—features Standard Technology (ST) pipetting tools, rapid on-the-fly tool swapping, and award-winning Volume-Verified Pipetting (VVP). With linear-motor motion and flexible deck designs, it delivers unmatched precision, throughput, and workflow integration.

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Gene Expression and Molecular CloningMolecular cloning is a set of techniques that utilizes vectors to transfer recombinant DNA into host cells and is an essential tool for investigating the expression of genes and proteins in bacterial or mammalian cells. A variety of vectors optimized for gene cloning and expression in a range of host organisms are available, alongside competent cells for genetic replication. Here, you can explore a range of molecular tools, high-quality genomic and cDNA libraries, premade clones, transformation and transfection reagents and mutagenesis or gene expression detection assays and expression arrays. Find the best gene expression and molecular cloning products in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Plasmid PurificationSLASThe Society for Laboratory Automation and Screening (SLAS) is an organization focused on laboratory automation, high-throughput screening, and biotechnology innovation. SLAS promotes scientific advancements through conferences, publications, and industry collaborations.