OGT’s miRNA profiling service provides rapid answers for disease research

13 May 2008

Product news

Oxford Gene Technology (OGT), the pioneer of microarray-based technologies, is pleased to announce the launch of a new microRNA (miRNA) profiling service designed to help researchers accelerate their discoveries. The flexible and cost-effective service offers high quality, customisable microarrays with the most up-to-date miRNA probe sequences, providing data from samples in just a few days.

In developing this service, OGT has co-funded the design of novel miRNA microarrays with the MolPAGE project (Molecular Phenotyping to Accelerate Genomic Epidemiology), a pan European consortium co-ordinated by Oxford University that focuses on diabetes and vascular disease. MicroRNAs are thought to be influential in the onset of diabetes and there is growing interest in their regulation of processes such as glucose homeostasis, insulin secretion and adipocyte differentiation. This new microarray will be used to measure the expression levels of mature miRNA and miRNA star sequences (miRNA*) in biomarker discovery samples.

Dr Mike Evans, Chief Executive at OGT said: ”OGT aims to be at the forefront of emerging technology and welcomes the opportunity to network with leading scientists in Europe. Our multi-array methodology allows for up to sixteen samples to be tested per slide, and has been optimised for high specificity, reproducibility, and low inter-array variability. The arrays are suitable for diverse studies in several eukaryotic species.”

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Genome AnalysisGenomics, the study of genomes, includes functional genomics, evolutionary genomics and comparative genomics. There are many genomic technologies such as DNA sequencing of whole genomes, computational biology and bioinformatics. DNA and nucleic acids must be isolated and concentrated from cells for analysis with kits, automated analyzers and software. Other useful technologies for studying genomics include PCR, microarrays and electrophoresis.Microarray AnalysisMicroarrays, also known as biochips, are used for the detection and analysis of multiple genes, proteins, antibodies, or biomarkers on a single microchip. This can reveal information on protein or gene expression, single nucleotide polymorphism (SNP), copy number variation (CNV), epigenetics and patient health in clinical diagnostic tests. Discover a range of microarray scanners and prefabricated antibody, protein, RNA and DNA microarrays for your analysis or consider creating your own custom microarrays with a microarray printer. Find the best microarray products in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.BiomarkersBiomarkers are biological markers which can be measured and evaluated to indicate a biological state. The use of biomarkers in research and diagnosis can indicate a normal or disease state or drug response of cells / tissues. Biomarkers include genetic markers, cell surface markers such as antigens, antibodies or receptors and secreted molecules such as cytokines. An assay system is required for identification of biomarkers. :
OGT’s miRNA profiling service provides rapid answers for disease research