Novel solid phase methodology accelerates peptide synthesis

A technical poster, available from Activotec, describes a novel all-solid phase approach for synthesising cyclic peptide chitinase inhibitors as potential new leads for antifungal and anti-inflammatory drugs.

Based upon work by UK researchers from the Department of Pharmacy & Pharmacology, University of Bath and the College of Life Sciences, University of Dundee the poster describes how the entirely on-resin synthesis on the Activo-P11 Peptide Synthesizer delivers significant improvements in speed and efficiency over traditional approaches.

The Activo-P11 Peptide Synthesizer is an easy to use and affordable instrument for synthesis of very high quality peptides. The fully automated and enclosed system performs a wide range of chemistries to synthesise peptides of any length in the 0.1 - 1.0 mmol. scale. Combined with very easy-to-use software, designed by chemists for chemists, the Activo-P11 was one of the most visited attractions at the exhibition accompanying the symposium.

Activotec is a peptide synthesis company providing innovative custom peptide synthesis services, peptide synthesizers and chemicals for chemical research and development. Founded in 2002, as a spin out from the University of Southampton, Activotec offers scientists around the world a single point of expertise and assistance in their research, design and manufacture of new, innovative and practical peptides. For further information on the Activo-P11 peptide synthesiser or a copy of the technical poster please contact Activotec.