Nonlinear Dynamics’ SameSpots approach becomes fastest selling 2D software

24 Jul 2006
Kerry Parker
CEO

Product news

Nonlinear Dynamics Ltd, a leading global provider of bioinformatics solutions, today announced that the uptake of the new SameSpots approach for 2D image analysis has made it Nonlinear’s fastest ever selling 2D analysis software. Released in March 2006, sales of SameSpots licenses in the first quarter of 2006/07 have exceeded those sold in the first 18 months after the initial launch of Progenesis.

SameSpots offers proteomics researchers a major breakthrough in the analysis of 2D single stain and DIGE images. This unique approach offers users a streamlined, faster 2D workflow, largely through the elimination of post analysis editing (on the majority of experiments). This drastically speeds up the 2D analysis process and reduces the subjectivity which editing inevitably introduces. The SameSpots approach also guarantees 100% matching across an experiment and no missing values, allowing increased statistical power and new possibilities for 2D based proteomics research.

These benefits have been extremely well received by proteomics researchers, who in the past have had to persevere with the inherent challenges of 2D image analysis. The customers who are benefiting from the new SameSpots technology span the academic, pharmaceutical and biotech industries.

At the time of writing the latest placement of this exciting technology has been at the Medical University of Vienna. Christopher Gerner, Associate Professor of Medical Biochemistry said “The SameSpots option is simply wonderful and I am so happy because it makes life so much easier for us! Currently we finalise several large 2D projects and spend so much time to find the significant alterations - which will be so much easier from now on. To give you an estimation spot correction based on detection and comparison to a reference gel took about 3-6 hours per gel. Now we only need to align the gel, which takes us about 30-45 min per gel.”

Will Dracup, CEO of Nonlinear Dynamics said, “The speed at which customers have converted to the SameSpots approach indicates the impact of this new technology in the proteomics marketplace. The range of benefits that SameSpots offers has the potential to re-invent 2D electrophoresis as the application of choice for proteomics research. This technology is being continually developed, for example we are about to roll out a semi-automated image alignment tool which makes analysis using SameSpots even faster. The future of 2D electrophoresis as the key proteomics application has never looked brighter.”

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ElectrophoresisElectrophoresis equipment is used to separate mixtures of protein, DNA or RNA, based on their electric charge, size and other physical characteristics, by passing them through a medium such as a polyacrylamide gel, an agarose gel or a capillary tube. Electrophoresis equipment includes horizontal and vertical gel electrophoresis chambers, isoelectric focusing systems, 2D electrophoresis and capillary electrophoresis instruments. Precast gels with a gradient can be used or gels can be hand cast. Samples are run alongside ladders or markers to identify the approximate size of a molecule. Separated proteins and nucleic acids in the gel can be stained or probed with fluorescent markers and then imaged and detected using gel documentation instruments, transilluminators, densitometers and scanners. Find the best electrophoresis equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.ProteomicsProteomics is the systemic bioinformatics study of proteins and amino acids, including their structure, size, function and identification. Tools used in proteomics include chromatography, blotting and gels, protein arrays, mass spectrometry and ELISA and associated analysis software. Analyzers and proteomic systems should be sensitive, high resolution, fast and may be automated for high-throughput.Data AnalysisData analysis hardware and software is available to make data processing straight-forward yet powerful. Data software can be used for math and stats, technical graphing and image analysis. In addition, software is available for specific data analysis of electrophoresis, densitometry, ELISA and DNA sequencing.Gel Doc / Image AnalysisGel documentation (gel doc) or gel imaging systems are used for the analysis of proteins, antibodies and nucleic acid immobilized in polyacrylamide or agarose gels, membranes or microarrays. Explore a range of a gel imaging systems, densitometers, scanners, transilluminators or UV lamp + CCD cameras for your image analysis solutions. Colorimetric, fluorescent and/or radioisotopic samples can be visualized and documented for further analysis. See gel doc / Image analysis software for quantitative 1D and 2D analysis of your samples. Find the best gel doc / image analysis products in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.