SelectScience
Join Free
Accelerating Science
NewsSeparations

Nonlinear Dynamics rolls out new strategy for proteomics

4 Apr 2007

Product news

Nonlinear Dynamics Ltd, a leading global provider of bioinformatics solutions, is rolling out a brand new strategy that enables the use of multiple techniques in proteomics research. A range of new products is being launched at ABRF 2007, Tampa, Florida, to support this new strategy.

Recent publications have highlighted that the overlap between 2D and LC-MS for proteomics analysis can be as little as 10%, consequently researchers should use both techniques for more complete coverage. Furthermore, the use of correct statistical tests is vital to ensure valid scientific conclusions are drawn. Nonlinear has expanded its Progenesis range to provide researchers with the analysis tools to achieve this goal.

Progenesis SameSpots for 2D image analysis was released last year and has received an overwhelming response from proteomics researchers. Version 2.0 is the definitive version with many new features to give even greater improvements in speed, objectivity and statistical power.

The launch of the Progenesis LC-MS expression analysis software, which utilises the advanced technology developed for the SameSpots approach, means users can apply the power of SameSpots to mass spec based proteomics and get the same benefits that this unique workflow delivers.

Progenesis Stats is an easy-to-use, multivariate statistical analysis tool that allows further interrogation of results generated from both Progenesis SameSpots and Progenesis LC-MS. It answers the key questions on complete data so researchers don’t miss biological changes which could be significant to their research.

Will Dracup, CEO of Nonlinear Dynamics said, “So far proteomics has struggled to provide results everyone believes that it should be capable of. We have been working on a strategy to help tackle this issue for years now and it’s great to be finally rolling it out both to our existing customers and to the many new customers who are switching to Nonlinear software. We are committed to driving proteomics into a new era and these new products underline that commitment.”

Tags

LC-MSLC-MS (liquid chromatography-mass spectrometry) systems and equipment are used for separation and quantitative analysis of complex mixtures, combining liquid chromatography and mass spectrometry. Quantify proteins, contaminants, pesticides or screen for drug metabolites with a high level of sensitivity. LC-MS systems and equipment include reverse phase, normal phase and specialized columns integrated with various MS detectors such as time-of-flight (TOF), quadrupole, orbitrap or ion trap mass analyzers. LC-MS/MS instruments equipped with a qTOF or triple quadrupole analyzer give greater sensitivity and resolving power to your analysis. Find the best LC-MS equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.ProteomicsProteomics is the systemic bioinformatics study of proteins and amino acids, including their structure, size, function and identification. Tools used in proteomics include chromatography, blotting and gels, protein arrays, mass spectrometry and ELISA and associated analysis software. Analyzers and proteomic systems should be sensitive, high resolution, fast and may be automated for high-throughput.Gel Doc / Image AnalysisGel documentation (gel doc) or gel imaging systems are used for the analysis of proteins, antibodies and nucleic acid immobilized in polyacrylamide or agarose gels, membranes or microarrays. Explore a range of a gel imaging systems, densitometers, scanners, transilluminators or UV lamp + CCD cameras for your image analysis solutions. Colorimetric, fluorescent and/or radioisotopic samples can be visualized and documented for further analysis. See gel doc / Image analysis software for quantitative 1D and 2D analysis of your samples. Find the best gel doc / image analysis products in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Chem / BioinformaticsCheminformatics and bioinformatics are computational techniques used in chemistry and biology, respectively, for data acquisition, processing and storage. Cheminformatics focuses on compound information, whereas bioinformatics is mainly applied to analysis and modeling of genomics, genetic and sequencing information. Hardware and software is available for data acquisition, analysis, management and storage.Data MiningData mining is an important process for extracting information, patterns and trends from data. Data mining software, databases, reference materials and storage packages are available to process lab data.

Related articles

Nonlinear Dynamics rolls out new strategy for proteomics