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Nikon Introduces Streamlined A1 MP Imaging System

Nikon Healthcare Business – Microscope Solutions
2 May 2011
bridget bridget
Laboratory Director

Product news

In response to demand, Nikon has developed a streamlined version of its groundbreaking A1R MP multiphoton confocal imaging system.

The new A1 MP scanner has been developed for simplified, cost-effective multiphoton imaging, whilst maintaining the sensitivity and quality of the highly respected A1R MP system. Multiphoton imaging is becoming increasingly popular for cell-friendly, dynamic live cell and deep tissue imaging. Budgetary constraints have, historically, prevented some laboratories from realising the full potential of this exciting technique.

Fluorescence detection is undertaken by Nikon’s highly sensitive NDD detectors (Non Descan Detectors). The scanner is capable of frame rates up to 10 fps, depending on image size and can easily be upgraded to true spectral imaging using Nikon’s renowned spectral detector.

The A1 MP imaging system can be used in conjunction with Nikon’s upright FN1 microscope and inverted Nikon Ti-E microscope, where it can also be combined with a TIRF system and incorporated with the award winning Perfect Focus System for long term, deep tissue imaging with unsurpassed clarity and stability.

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Cell-Based AssaysCell-based assays are used to monitor the presence, quantity and activities of a desired cellular analyte including drug molecules or biomarkers. This can reveal information on cell health (apoptosis, cytotoxicity, viability and proliferation assays), cell metabolism, cell migration and cell signaling mechanisms. Find the best cell-based assay products, kits and equipment with our peer reviewed product directory: compare products, check customer reviews and receiving pricing direct from manufacturers.Protein PurificationProtein purification is a vital step in drug discovery, therapeutics, biotech and life science research. The purification process typically involves subcellular or membrane protein extraction with cell lysis kits, separation of proteins from cell debris by filtration or spin columns, and the isolation of proteins of interest from other proteins and impurities with affinity purification (including fusion protein tags and antibody binding proteins A, G and L), immunoprecipitation or chromatographic methods, such as ion exchange, size exclusion and immobilized metal affinity chromatography. All purification methods come in multiple formats for your laboratory needs, including agarose or magnetic beads, resins, columns and filter plates. Find the best protein purification equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.BiomarkersBiomarkers are biological markers which can be measured and evaluated to indicate a biological state. The use of biomarkers in research and diagnosis can indicate a normal or disease state or drug response of cells / tissues. Biomarkers include genetic markers, cell surface markers such as antigens, antibodies or receptors and secreted molecules such as cytokines. An assay system is required for identification of biomarkers. :In Vivo Imaging Systems<i>In vivo</i> imaging systems, including pre-clinical imaging systems and medical imaging systems are used to non-invasively visualize and capture images of live animals and plants. Monitor the natural processes or diseases of your subjects using small-animal pre-clinical imaging systems, including single photon positron emission tomography (SPECT), positron emission tomography (PET), computed tomography (micro-CT), magnetic resonance imaging (MRI), X-ray radiography, ultrasound, fluorescence and bioluminescence imagers. Multimodal systems and software solutions are also available for correlative analysis of organ, tissue, cell, or molecular-level processes. Find the best in vivo imaging products in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Light MicroscopyLight microscopes or optical microscopes are used to visualize microscale objects under magnification, including cells, clinical specimens and materials. Lab equipment for light microscopy includes confocal microscopes, fluorescence microscopes, zoom and stereo microscopes. Microscope slides and imaging reagents are available for visualizing samples, as well as various microscope stages and incubators for large or temperature-sensitive samples. Find the best light microscopes in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.

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Nikon Introduces Streamlined A1 MP Imaging System