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Nicoya launches Alto Automation Suite to facilitate SPR integration into high-throughput biologics discovery workflows

Nicoya

Nicoya presented its new biosensor technology innovation at SLAS2025 International Conference & Exhibition

4 Feb 2025

Product news

Nicoya® has launched the Alto Automation Suite™ for its flagship Alto™ Digital SPR™ system. The Alto is a surface plasmon resonance (SPR) platform that is fully compatible with standard lab automation, enabling thousands of samples per week to be run without human intervention.

A robotic arm retrieves the Alto Cartridge, filled with samples and reagents, from the Opentron Flex liquid handling platform and transfers it to the Nicoya Alto Digital SPR system.

The Alto Automation Suite features an API to allow scientists to program tasks for the Alto and to facilitate its integration with existing automated workflows, LIMS systems, and data pipelines. Nicoya has also partnered with Opentrons to offer pre-configured labware definitions and workflows to streamline cartridge preparation on the Opentrons Flex® liquid handling robot.

"With the rapid evolution of AI in protein design, it’s becoming increasingly important to streamline high-throughput biologics characterization by automating and integrating workflows via software and hardware,” said Ryan Denomme, CEO at Nicoya. “Incorporating SPR into these workflows has traditionally been a significant challenge. Conventional SPR systems are bulky, complex, and require constant manual intervention to keep buffers replenished and to change out sensor chips. With Alto’s compact, robot-compatible design, unique well-plate-based cartridges, and cloud-native software, we’ve eliminated these barriers, enabling 24/7 unattended SPR analysis.”

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BiosensorsBiosensors are devices used to detect an analyte using biological molecules specific to the analyte coupled to a detector. Biosensor instruments may be photometric, typically using surface plasma resonance (SPR), electrochemical or QCM (quartz crystal microbalance) biosensors. Biosensors should be selective, portable, robust and sensitive and have a fast response time. Systems may be manual or automated and usually have associated software.Artificial Intelligence / Machine LearningArtificial intelligence (AI) and machine learning (ML) are transformative technologies used to analyze complex data, identify patterns, and make data-driven predictions across diverse scientific fields. Automate the analysis of large or complex data sets using AI algorithms and leverage machine learning models to improve diagnostics, accelerate drug discovery, and refine experimental design. Discover the best AI/ML software, platforms, and analytical tools in our peer-reviewed product directory: compare features, read customer reviews, and request pricing directly from manufacturers.Robotic InstrumentsRobotic instruments can be used for high-throughput automation of many lab processes. Such processes use instruments for assays like cell based assays and ELISA, for sample preparation like shakers, centrifuges and incubators, and for analysis such as sequencing and western blot analyzers. Useful features of robotic instruments include speed, reproducibility, barcode readers, software and automation.Surface Plasmon ResonanceSLASThe Society for Laboratory Automation and Screening (SLAS) is an organization focused on laboratory automation, high-throughput screening, and biotechnology innovation. SLAS promotes scientific advancements through conferences, publications, and industry collaborations.

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Nicoya launches Alto Automation Suite to facilitate SPR integration into high-throughput biologics discovery workflows