Next-Generation Kinetex® Calculator for Customized HPLC Method Creation

29 Nov 2011
Roger Wayman
Administrator / Office Personnel

Product news

Phenomenex Inc. has introduced the next-generation Kinetex Calculator – an online tool that generates customized, optimized Kinetex methods for HPLC or UHPLC systems.

With user input, which is entered online, the Calculator quickly produces an optimized method based on the customer’s own running conditions. The enhanced Calculator incorporates all six Kinetex phases, including the new phenyl-hexyl chemistry, and will calculate a new gradient program to account for differences in column dimensions and adjustments in running conditions. Customers may also now adjust parameters such as flow rate, column length, I.D. and backpressure and quickly see a revised, optimized method.

The Kinetex Calculator helps users apply advanced core-shell technology to their current methods to produce better results, increase sample throughput and decrease solvent consumption.

Along with the method, the online tool calculates the improvements the user can expect by switching to Kinetex core-shell technology columns. Predicted solvent, time and total cost savings, projected over 1,000 samples, are provided.

“This next-generation tool saves time, eliminates guess work, and gets users up and running with Kinetex core-shell technology,” explains Jeremy Bierman, brand manager for Phenomenex. “The new functionality that enables customers to adjust parameters gives them an even higher degree of accuracy and comfort in their specific analyses.”

Kinetex core-shell technology meets researchers’ needs to improve results and increase productivity without large capital expenditures. Kinetex delivers increases in speed and separation efficiency over traditional, fully porous columns, enabling chromatographers to get UHPLC results on any HPLC instrument.

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UHPLC and HPLCHigh performance liquid chromatography (HPLC) and ultra high performance liquid chromatography (UHPLC), also known as UPLC, are analytical techniques used to separate, identify and quantitate components of complex mixtures including biological samples such as proteins and lipids as well as chemical mixtures of pesticides, drugs and oils. Both techniques are liquid chromatographic methods but differ by operating pressures (HPLC < 6000 psi < UHPLC ). Components of HPLC and UHPLC systems include columns, detectors, pumps, autosamplers and column heaters. Explore a range of UHPLC and HPLC columns for your specific sample needs including reverse phase, normal phase, ion exchange, HILIC, ion exclusion and size exclusion columns. For more specialized HPLC, explore FPLC, countercurrent LC and simulated moving bed systems. Find the best UHPLC and HPLC equipment in our peer reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Software PlatformsSoftware platforms are useful for various stages of laboratory experiments from data collection to data storage and processing. For instance lab software is available for system control, data management, data analysis and qualification / validation.Core-Shell Technology
Next-Generation Kinetex® Calculator for Customized HPLC Method Creation