New Whitepaper Discusses How Best to Utilise Next Generation Techniques for Genomic Research

2 Aug 2011

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Oxford Gene Technology (OGT), provider of innovative clinical genetics and diagnostic solutions to advance molecular medicine, has released a new white paper discussing the relative merits of DNA microarrays and next generation sequencing (NGS) for human genome analysis. Although the development of genome analysis technologies such as DNA microarrays and NGS has provided the researcher with the unique ability to screen for sequence variants of clinical relevance, each technology has its own unique advantages, meaning that choosing the most appropriate technology for any given study can be challenging. Therefore, the resulting whitepaper, which can be downloaded via the 'company article' link on the right hand side, discusses the essential factors to consider when selecting the optimal platform for a specific study.

The white paper discusses issues such as the suitability of microarrays and sequencing for various applications, the relative costs associated with each technology and how to overcome the challenges posed by the analysis of large and complex datasets.

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Genome AnalysisGenomics, the study of genomes, includes functional genomics, evolutionary genomics and comparative genomics. There are many genomic technologies such as DNA sequencing of whole genomes, computational biology and bioinformatics. DNA and nucleic acids must be isolated and concentrated from cells for analysis with kits, automated analyzers and software. Other useful technologies for studying genomics include PCR, microarrays and electrophoresis.Microarray AnalysisMicroarrays, also known as biochips, are used for the detection and analysis of multiple genes, proteins, antibodies, or biomarkers on a single microchip. This can reveal information on protein or gene expression, single nucleotide polymorphism (SNP), copy number variation (CNV), epigenetics and patient health in clinical diagnostic tests. Discover a range of microarray scanners and prefabricated antibody, protein, RNA and DNA microarrays for your analysis or consider creating your own custom microarrays with a microarray printer. Find the best microarray products in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Gene Expression and Molecular CloningMolecular cloning is a set of techniques that utilizes vectors to transfer recombinant DNA into host cells and is an essential tool for investigating the expression of genes and proteins in bacterial or mammalian cells. A variety of vectors optimized for gene cloning and expression in a range of host organisms are available, alongside competent cells for genetic replication. Here, you can explore a range of molecular tools, high-quality genomic and cDNA libraries, premade clones, transformation and transfection reagents and mutagenesis or gene expression detection assays and expression arrays. Find the best gene expression and molecular cloning products in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.
New Whitepaper Discusses How Best to Utilise Next Generation Techniques for Genomic Research