New Webinar on Oncology Applications of RAFT 3D Cell Culture

22 Oct 2013
Emily Marquez-Vega
Publishing / Media

Product news

TAP Biosystems, a leading supplier of innovative cell culture systems and consumables for life science applications, today announced that it will be running a new webinar on Wednesday November 6th, offering free access to scientific presentations on the benefits of using its innovative RAFT™ 3D collagen-based cell culture technology in oncology research.

Two 3D cell culture experts, Dr Marilena Loizidou, Senior Lecturer in Cancer Nanotechnology at UCL Division of Surgery and Interventional Science and Dr Grant Cameron, RAFT Development Director at TAP Biosystems will be presenting data on the RAFT 3D cell culture technology and how it can be utilised to improve results in a number of pre-clinical oncology research applications at two, live webinars on Wednesday November 6th at 11am GMT and 4pm GMT.

During the hour long webinars, Dr Loizidou will discuss how 3D cancer cultures are emerging as a more pathologically-relevant in vitro model than 2D cultures, and how they can be engineered using the RAFT collagen-based technology to mimic the tissue heterogeneity of in vivo solid tumours. Dr Loizidou will also present data on how RAFT generated 3D cancer models can be used for therapeutic investigations or developed as imaging phantoms.

Dr Cameron will discuss the use 3D collagen based cell cultures to produce dose response curves and to study cell signalling, target modulation and mitochondrial function with data comparisons between 2D cell culture techniques and RAFT generated 3D cell cultures. Dr Cameron will also provide a brief overview of additional application areas where 3D cell culture is adding value such as improving maturation of iPS hepatocytes over extended culture periods.

Dr Grant Cameron, TAP Biosystems’ RAFT Development Director explained: “There is an increasing demand for realistic 3D cell culture models in oncology research because working with a more physiologically relevant, reproducible cellular environment has the potential for reducing risk in oncology screening by improving translational results.”

Cameron added: “I am privileged to be hosting a webinar alongside such a well respected oncology expert as Dr Marilena Loizidou. It is a great opportunity for existing 3D cell culture advocates and researchers evaluating 3D cell culture to meet. We look forward to discussing the benefits of routinely incorporating the RAFT 3D cell culture process into oncology screening programmes with scientists that join us for these informative webinars on November 6th.”

RAFT (Real Architecture for 3D Tissue)

TAP Biosystems

RAFT is a new 3D cell culture system that enables scientists to create complex 3D tissue models in a simple, consistent and reproducible format. RAFT uses physiologically relevant collagen concentrations to create the most natural environment for cells. RAFT enables scientists to create 3D cell cultures in 3 simple steps in less than 1 hour. RAFT can be used to support assay development and secondary screening applications. It can also be used in a broad range of cell biology applications including: stem cell research, oncology research, toxicology and tissue engineering / scaffolds.

(0)

Links

Tags

Cell Adhesion AssaysCell adhesion assays are used to quantitate attachment and analyze the molecular mechanisms for extracellular matrix adhesion, cell migration and sensitivity to inhibitors. Find the best cell adhesion assay equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Cell / Tissue CultureCell culture or tissue culture is used to study the biology of cells or tissues and to isolate cellular products in an environment which can be manipulated and well defined. Accurately control your culture environment with bioreactors or culture incubators, bind your cells to a surface or together with an extracellular matrix. Distinguish cell types with differential media or proliferate cells with certain characteristics using selective media. Enrich your media with supplements such as growth factors, sera and vitamins. Find the best cell and tissue culture products, kits and equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Cell Lines Stem Cells and Primary CellsPrimary cell cultures, established cell lines and stem cells are vital for <i>in vitro</i> and <i>ex vivo</i> experimentation. High-quality cells, optimized for your applications, alongside optimized cell substrates, growth medium and supplements, are critical for experimental success. Explore a range of cells suitable for your applications, including isogenic cell lines, competent cells, induced pluripotent stem cell (iPSC)-derived cell lines, fungal/bacterial/mammalian cell lines, stem cells and cancer cell lines. Find the best cells for your research in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Cell-Based AssaysCell-based assays are used to monitor the presence, quantity and activities of a desired cellular analyte including drug molecules or biomarkers. This can reveal information on cell health (apoptosis, cytotoxicity, viability and proliferation assays), cell metabolism, cell migration and cell signaling mechanisms. Find the best cell-based assay products, kits and equipment with our peer reviewed product directory: compare products, check customer reviews and receiving pricing direct from manufacturers.OlympicsCancer ResearchAlthough cancer is often referred to as a single condition, it actually consists of more than 100 different diseases. Microscopy, mass spectrometry, high throughput sequencing and flow cytometry are some of the most common techniques employed in cancer research labs.