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New Ultra-Sensitive Multiple Protein Arrays Launched at the 13th Annual Biomarker and Diagnostic World Congress

Aushon BioSystems Inc.
1 May 2017
Lois Manton-O'Byrne, PhD
Executive Editor

Product news

Aushon BioSystems, a leading provider of high sensitivity assays, instrumentation and services for multiplex quantitative detection of protein biomarkers, today announced the launch of the Ciraplex ULTRA Ultrasensitive Human 3-Plex IL-1β, IL-6, IL-10 Multiplexed Assay.

“We believe the ability to combine ultrasensitive detection with multiplexing will change the way clinicians use biomarkers to diagnose and treat diseases”, said Susan Vogt, CEO of Aushon. “As we work closely with our clinical partners, Aushon continues to be committed to advancing multiplexing capabilities for complex disease studies in the area of precision medicine.”

The new Aushon Ciraplex ULTRA Ultrasensitive Human 3-Plex IL-1β, IL-6, IL-10 Multiplexed Assay is a plate based protein array with ability to obtain low levels of detection for up to 3 biomarkers in one assay. The new product advancement allows clinician’s with precious samples to measure biomarkers simultaneously, rather than sequentially, thus optimizing sample consumption. The ultra-sensitivity is measured at single-digit femtogram/ml (fg/ml) levels which are unmatched by other standard protein immunoassay methods.

“Low levels of detection are the cornerstone of our Ciraplex ULTRA line of assays”, said Scott Van Arsdell, Ph.D., Vice President, Immunoassay Technology. “The new 3-Plex assay enables clinical researchers to detect very low levels of cytokines in their samples which would not be possible before. The real advantage is having the confidence that you can run one sample and obtain reliable, quantifiable results for multiple biomarkers. “

In conjunction with the launch of the Ciraplex ULTRA Ultrasensitive 3-Plex Assay, Andrew Nixon, PhD., Professor of Medicine and Director of the Duke Phase I Biomarker Laboratory, Molecular Reference Lab, Duke University will present data at the Biomarkers and Immuno-Oncology World Congress in Philadelphia on Wednesday, May 3, 2017 at 8:25AM. Dr. Nixon will show technical data and patient data from samples run on the new Aushon Ciraplex Human Cytokine 10-plex Array and Ciraplex ULTRA Ultrasensitive 3-plex kit demonstrating the use of ultrasensitive multiplex protein arrays in immuno-oncology biomarker development.

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Aushon BioSystems Inc.Company website

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Protein PurificationProtein purification is a vital step in drug discovery, therapeutics, biotech and life science research. The purification process typically involves subcellular or membrane protein extraction with cell lysis kits, separation of proteins from cell debris by filtration or spin columns, and the isolation of proteins of interest from other proteins and impurities with affinity purification (including fusion protein tags and antibody binding proteins A, G and L), immunoprecipitation or chromatographic methods, such as ion exchange, size exclusion and immobilized metal affinity chromatography. All purification methods come in multiple formats for your laboratory needs, including agarose or magnetic beads, resins, columns and filter plates. Find the best protein purification equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.BiomarkersBiomarkers are biological markers which can be measured and evaluated to indicate a biological state. The use of biomarkers in research and diagnosis can indicate a normal or disease state or drug response of cells / tissues. Biomarkers include genetic markers, cell surface markers such as antigens, antibodies or receptors and secreted molecules such as cytokines. An assay system is required for identification of biomarkers. :ImmunologyImmunological techniques measure and characterize immune responses. Immunology kits and analysis systems often use techniques such as ELISA, radioimmunoassay (RIA) and immunodiffusion assays, Immunohistochemistry, and flow cytometry. Immunologists use equipment such as flow Cytometers, plate readers, plate washers and fluorescent microscopes.ImmunoassayImmunoassays are laboratory tests that utilize antibody-antigen interactions to detect specific substances. They are widely used in diagnostics for detecting diseases, drug testing, and environmental monitoring. These assays offer rapid, sensitive, and precise detection of biomarkers, making them invaluable in clinical and research labs. Browse our peer-reviewed product directory to compare immunoassay systems, read user reviews, and get pricing directly from manufacturers.Cancer DiagnosticsThere are a wide variety of diagnostic tests for cancer available, and this range continues to expand as our knowledge of cancer improves. Current diagnostic methods include biopsy, imaging and blood tests for known biomarkers. New methods in research development include liquid biopsies and cancer breathalyzers.MultiplexAntibody ArraysCancer ResearchCancer research aims to understand the mechanisms of cancer development and progression to improve prevention, diagnosis, and treatment. From molecular biology to clinical trials, research spans a wide range of disciplines, including immunotherapy, targeted therapies, and drug discovery. Explore the best cancer research products in our peer-reviewed product directory; compare products, check reviews, and get pricing directly from manufacturers.Protein BiologyBiomarker DiscoveryClinical biomarkers refer to substances related to known medical conditions that can be accurately measured <i>in vitro</i>. Biomarkers can be used to diagnose presence of a disease and indicate disease severity. The discovery of new biomarkers is incredibly valuable in the field of diagnostics.

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New Ultra-Sensitive Multiple Protein Arrays Launched at the 13th Annual Biomarker and Diagnostic World Congress