New Technologies that Enhance Cell-based and Label-Free Microplate Assays Will Be Highlighted at Miptec 2012

9 Sept 2012

Product news

BMG LABTECH is proud to be a Silver Sponsor of the annual Miptec meeting in Basel, Switzerland from September 24th-27th 2012. BMG LABTECH - The Microplate Reader Company - will showcase its newest technology at Miptec 2012, detailing how this technology greatly enhances applications. Stop by Booth #A22 to see unique and proprietary microplate reader technology that separates BMG LABTECH instruments from all of the rest.

As will be highlighted in several posters and at an Industry Symposium, BMG LABTECH will detail how its microplate reader technologies can improve your scientific research. When designing its newest microplate readers, BMG LABTECH analyzed the market to determine what features are missing in a microplate reader that will enhance life science applications. Two such advancements that greatly improve assays are ultra-fast, full spectrum analysis for absorbance assays and Direct Optic Bottom Reading for cell-based assays.

In the Industry Symposium on Tuesday afternoon September 25th, in conjunction with Labcyte and CISBIO, BMG LABTECH will show how its Direct Optic Bottom Reading can create an automated cell-based HTS screening platform that compliments or rivals slower HCS platforms. See how these three companies have brought together their technologies to create such a platform. With Direct Optic Bottom Reading on the PHERAstar FS, the signal-to-blank ratio in fluorescent cell-based assays like GFP, mCherry, and mOrange is more than 300% higher than on fiber optic plate readers. With this level of sensitivity, obtaining higher throughput from an existing FACS or a confocal microscope assay is now possible with this platform.

In addition, BMG LABTECH will highlight in a poster a new label-free system that can determine protein-protein binding kinetics using ultra-fast, full spectrum analysis in a spectrometer-based microplate reader. In collaboration with PharmaDiagnostics, a label-free system that uses their SoPRanoTM label-free technology and a BMG LABTECH spectrometer-based microplate reader has been designed. Without the need to purchase expensive and dedicated equipment, this label-free system can quickly analyze and determine the KD values, EC/IC50s, as well as the association (ka) and dissociation (kd) rates for a protein-protein interaction.

Please visit BMG LABTECH at Booth #A22 at Miptec 2012 to learn more about the future of microplate reader technology today.

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MicroplatesMicroplates are multi-well plates used to increase the throughput of biological investigations. The number of wells microplates contain can range from 6 to 3243 wells, with the 96-well format being the most commonly used. Microplates can come tailored for a range of applications including cell culture, PCR, filtration, storage, non-binding surface, protein crystallization, as well as pre-coated, deep well and normal Standard microplates. Additionally, options for microplate colors include clear , black, white or black with clear bottom and white with clear bottom for absorbance microplate reader applications. Find the best microplates for your lab in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Microplate Readers / DetectorsMicroplate readers are used to automate the detection and analysis of labeled or label-free components in microplates during assays or live-cell monitoring. Microplate readers are generally distinguished by their mode of detection. Types include absorbance, luminescence, fluorescence intensity, fluorescence polarization, TRF / FRET and multimode microplate readers. Microplate readers deliver a high throughput of samples by reading multiple wells simultaneously, with the 96-well format the most commonly used. As a result, microplate readers are often used in the drug discovery, bioassays, research and pharmaceutical industries for screening applications. Microplate loading can also be automated, with robotic microplate stackers to increase throughput. Find the best microplate readers in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.MipTec
New Technologies that Enhance Cell-based and Label-Free Microplate Assays Will Be Highlighted at Miptec 2012