SelectScience
Join Free
Accelerating Science
NewsLife Sciences

New Range of Conjugated Polymer Nanoparticles (CPNs) Could Revolutionize Diagnostics and Therapeutics

Stream Bio Ltd

Stream Bio launches new range of Streptavidin-linked CPNs

12 Dec 2018
Frankie MacDonald
Administrator / Office Personnel

Product news

Stream Bio, a company that develops and manufactures a range of revolutionary bioimaging molecular probes, has launched its new range of Streptavidin-linked CPNs™ onto the market. These Streptavidin Conjugates can be used for the detection of various biomolecules and will complement Stream’s current portfolio of CPN molecular probes.

Stream Bio’s CPNs have applications in diagnostics and therapeutics, and have the potential to be used for imaging tumours and fluorescence-guided surgery. These highly fluorescent, non-toxic nanoparticles are set to transform the bioimaging market with their unique brightness, exceptional stability, magnetic capability and suitability to be conjugated with a wide variety of molecules.

The new range of molecular probes from Stream Bio have streptavidin covalently attached to fluorescent CPNs. This allows the intense fluorescence of the CPN to be readily linked to a wide array of targeting molecules. Streptavidin is a protein with an extraordinarily high binding affinity for biotin and is commonly used to link fluorophores to primary or secondary antibodies for specific detection of a variety of proteins, protein motifs, nucleic acids, and other biomolecules. Some of the detection protocols the Streptavidin-linked CPNs™ can be used with include flow cytometry, Western Blots, microplate assays, imaging and microscopy.

The Streptavidin linked CPNs are available in four wavelengths; 475nm, 510nm, 550nm and 680nm. They can be purchased from distributors 2B Scientific in the UK, Clinisciences in France, and Biotrends in Germany.

Andrew Chaloner, Founding Director and CEO of Stream Bio, commented: “We are delighted to be releasing our most recent range of CPNs. Seeing our products develop and be successfully brought to market is a justification of all the hard work put in by the team here at Stream Bio. I am excited to see the opportunities that this new range will bring and what the future holds for our products.”

Visit the SelectScience Life Sciences Community for more news and resources>>

Links

Stream Bio LtdCompany website

Tags

BiosensorsBiosensors are devices used to detect an analyte using biological molecules specific to the analyte coupled to a detector. Biosensor instruments may be photometric, typically using surface plasma resonance (SPR), electrochemical or QCM (quartz crystal microbalance) biosensors. Biosensors should be selective, portable, robust and sensitive and have a fast response time. Systems may be manual or automated and usually have associated software.Cell / Tissue CultureCell culture or tissue culture is used to study the biology of cells or tissues and to isolate cellular products in an environment which can be manipulated and well defined. Accurately control your culture environment with bioreactors or culture incubators, bind your cells to a surface or together with an extracellular matrix. Distinguish cell types with differential media or proliferate cells with certain characteristics using selective media. Enrich your media with supplements such as growth factors, sera and vitamins. Find the best cell and tissue culture products, kits and equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Cell-Based AssaysCell-based assays are used to monitor the presence, quantity and activities of a desired cellular analyte including drug molecules or biomarkers. This can reveal information on cell health (apoptosis, cytotoxicity, viability and proliferation assays), cell metabolism, cell migration and cell signaling mechanisms. Find the best cell-based assay products, kits and equipment with our peer reviewed product directory: compare products, check customer reviews and receiving pricing direct from manufacturers.BiomarkersBiomarkers are biological markers which can be measured and evaluated to indicate a biological state. The use of biomarkers in research and diagnosis can indicate a normal or disease state or drug response of cells / tissues. Biomarkers include genetic markers, cell surface markers such as antigens, antibodies or receptors and secreted molecules such as cytokines. An assay system is required for identification of biomarkers. :In Vivo Imaging Systems<i>In vivo</i> imaging systems, including pre-clinical imaging systems and medical imaging systems are used to non-invasively visualize and capture images of live animals and plants. Monitor the natural processes or diseases of your subjects using small-animal pre-clinical imaging systems, including single photon positron emission tomography (SPECT), positron emission tomography (PET), computed tomography (micro-CT), magnetic resonance imaging (MRI), X-ray radiography, ultrasound, fluorescence and bioluminescence imagers. Multimodal systems and software solutions are also available for correlative analysis of organ, tissue, cell, or molecular-level processes. Find the best in vivo imaging products in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Light MicroscopyLight microscopes or optical microscopes are used to visualize microscale objects under magnification, including cells, clinical specimens and materials. Lab equipment for light microscopy includes confocal microscopes, fluorescence microscopes, zoom and stereo microscopes. Microscope slides and imaging reagents are available for visualizing samples, as well as various microscope stages and incubators for large or temperature-sensitive samples. Find the best light microscopes in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.NanotechnologyNanotechnology, or nanotech, is an engineering technique using molecular scale functional systems. Applications of nanotechnology include medicine and medical devices, electronics, air and water purification, food science and energy production.BiotherapeuticsBiotherapeutics are proteins and other compounds (such as nucleic acids) produced by living organisms that have uses as therapeutics or in <i>in vivo</i> diagnostics. The most well-known example of a biotherapeutic product, and the first to be approved for therapeutic use, was recombinant human insulin.In Vitro DiagnosticsIn vitro diagnostics (IVD) involve testing samples outside the body, typically in a laboratory, to diagnose diseases or conditions. IVD technologies include blood tests, molecular assays, and other bodily fluid tests, enabling accurate diagnosis and monitoring of diseases. These tests are essential for guiding treatment decisions in clinical settings. Browse our peer-reviewed product directory to find the best IVD solutions; compare products, check reviews, and get pricing directly from manufacturers.TherapeuticsTherapeutics are treatments designed to alleviate or cure diseases. These include pharmaceuticals, biologics, and gene therapies, which work by targeting specific disease mechanisms. Advances in personalized medicine and biologics offer new hope for patients with conditions that were previously difficult to treat. Browse our peer-reviewed product directory to find therapeutic solutions for various diseases; compare products, check user reviews, and get pricing directly from manufacturers.NanoparticlesNanoparticles are between 1-100nm in size. Nanoparticles can be used for a wide variety of applications including biomedical, catalysis and electronics.

Related articles