New QIAGEN® Products for Protein Science

26 Apr 2006
Kerry Parker
CEO

Product news

QIAGEN expands its protein product portfolio with new tools to streamline and simplify your protein research. Two new Qproteome kits provide apoptosis and cell signaling researchers with high-purity, highly active mitochondria and plasma-membrane protein preparations, virtually free of contaminating proteins from other cell compartments. Mass·Spec·Turbo Chips are ready-to-use targets prespotted with up to 1600 homogeneous matrix spots for high-throughput MALDI analyses.

A major challenge facing researchers studying individual cell compartments or organelles is obtaining pure fractions free of contaminating proteins from other compartments. Reproducible separation of mitochondria and cytosolic proteins is notoriously difficult. Traditional methods are tedious, time-consuming, and require access to an ultracentrifuge. Qproteome Mitochondria Isolation and Plasma Membrane Protein kits provide high-purity preparations with fully active proteins for apoptosis and cell-signaling assays and cellular localization studies.

Developed for high-throughput analysis, each ready-to-use Mass·Spec·Turbo Chip has up to 1600 homogeneous matrix spots, providing highly reproducible, high-resolution MALDI analysis of complex proteomics samples (e.g., liquid chromatography runs, 2D gels, etc.). By ensuring optimal presentation of samples, on-chip processing increases sensitivity and mass accuracy, making identification of low-abundance peptides easier and faster.

Links

Tags

UHPLC and HPLCHigh performance liquid chromatography (HPLC) and ultra high performance liquid chromatography (UHPLC), also known as UPLC, are analytical techniques used to separate, identify and quantitate components of complex mixtures including biological samples such as proteins and lipids as well as chemical mixtures of pesticides, drugs and oils. Both techniques are liquid chromatographic methods but differ by operating pressures (HPLC < 6000 psi < UHPLC ). Components of HPLC and UHPLC systems include columns, detectors, pumps, autosamplers and column heaters. Explore a range of UHPLC and HPLC columns for your specific sample needs including reverse phase, normal phase, ion exchange, HILIC, ion exclusion and size exclusion columns. For more specialized HPLC, explore FPLC, countercurrent LC and simulated moving bed systems. Find the best UHPLC and HPLC equipment in our peer reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.ProteomicsProteomics is the systemic bioinformatics study of proteins and amino acids, including their structure, size, function and identification. Tools used in proteomics include chromatography, blotting and gels, protein arrays, mass spectrometry and ELISA and associated analysis software. Analyzers and proteomic systems should be sensitive, high resolution, fast and may be automated for high-throughput.High-Throughput ScreeningHigh-throughput screening (HTS) is an automated drug discovery technique for identification of active compounds against a compound library. Use HTS readers and integrated assay preparation / analysis workstations to screen your compounds. Identify active compounds against various HTS libraries, including membranes, proteins and peptides and HTS cell lines. Find the best high-throughput screening products in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Gel Doc / Image AnalysisGel documentation (gel doc) or gel imaging systems are used for the analysis of proteins, antibodies and nucleic acid immobilized in polyacrylamide or agarose gels, membranes or microarrays. Explore a range of a gel imaging systems, densitometers, scanners, transilluminators or UV lamp + CCD cameras for your image analysis solutions. Colorimetric, fluorescent and/or radioisotopic samples can be visualized and documented for further analysis. See gel doc / Image analysis software for quantitative 1D and 2D analysis of your samples. Find the best gel doc / image analysis products in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Preparative ChromatographyPreparative chromatography equipment is used for purification purposes, separating and collecting compounds eluted from a mixture which can then be subsequently used for further purposes. This can be done in large quantities or small. Preparative chromatography systems are usually low to medium pressure liquid chromatographs that are semi-automated. Explore a range of preparative columns and fraction collectors. Find the best preparative chromatography equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Cell-Based AssaysCell-based assays are used to monitor the presence, quantity and activities of a desired cellular analyte including drug molecules or biomarkers. This can reveal information on cell health (apoptosis, cytotoxicity, viability and proliferation assays), cell metabolism, cell migration and cell signaling mechanisms. Find the best cell-based assay products, kits and equipment with our peer reviewed product directory: compare products, check customer reviews and receiving pricing direct from manufacturers.