New Products from Aureus Pharma: AurSCOPE® Global Pharmacology Space Plus New Drug Target Knowledge Databases Related to Nuclear Receptors and Proteases

17 Aug 2008

Product news

Aureus Pharma, a leading provider of knowledge management solutions that accelerate life sciences discovery, announced today the release of three new AurSCOPE® Target knowledge databases. The new offerings include knowledge databases for the important drug targets Nuclear Receptor and Protease, as well as the centralized product AurSCOPE® Global Pharmacology Space (AurSCOPE® GPS). AurSCOPE GPS comprises all of the pharmaceutically important therapeutic targets including G-Protein coupled receptors (GPCR), kinases, ion channels, nuclear receptors and proteases.

Nuclear receptor proteins are integral to critical metabolic processes and implicated in diseases including diabetes, cancer, and heart disease. Likewise, proteases are a major focus for therapeutic intervention being linked to viral diseases including HIV, inflammation and neurogenerative disorders.

AurSCOPE GPS and other AurSCOPE Knowledge databases streamline discovery efforts with thorough assessment of selectivity and off-target effects at the earliest stages of the drug discovery pipeline.

“The release of AurSCOPE Global Pharmacology Space (GPS), Nuclear Receptor and Protease represents an exciting milestone for Aureus Pharma. These powerful new products considerably extend Aureus’ knowledge management solution by providing our pharmaceutical customers unique access to the druggable therapeutic target space.” said Jason Theodosiou, President and CEO of Aureus Pharma. “Using AurSCOPE Knowledge databases, researchers can easily employ knowledge-driven hypotheses to drive better informed decisions during drug discovery.”

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High-Throughput ScreeningHigh-throughput screening (HTS) is an automated drug discovery technique for identification of active compounds against a compound library. Use HTS readers and integrated assay preparation / analysis workstations to screen your compounds. Identify active compounds against various HTS libraries, including membranes, proteins and peptides and HTS cell lines. Find the best high-throughput screening products in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Data AnalysisData analysis hardware and software is available to make data processing straight-forward yet powerful. Data software can be used for math and stats, technical graphing and image analysis. In addition, software is available for specific data analysis of electrophoresis, densitometry, ELISA and DNA sequencing.Data MiningData mining is an important process for extracting information, patterns and trends from data. Data mining software, databases, reference materials and storage packages are available to process lab data.Compound LibrariesCompound libraries, or chemical libraries, are used in drug discovery for the identification of potential therapeutics compounds. Used in conjunction with high-throughput screening, the libraries of stored compounds are often generated for specific purposes as a drug target or disease model. Cheminformatics are commonly used when designing a compound library and software can be used to analyze the screening process.  Biopharmaceutical AdvancesBiopharmaceutical advances follow the development of pharmaceuticals derived from biotechnology, also known as biotechnology medicines. Biopharmaceuticals may be produced from cell lines, plants, or microbial cells. Important considerations of biopharmaceutical use include application, cost, production process and purification.
New Products from Aureus Pharma: AurSCOPE® Global Pharmacology Space Plus New Drug Target Knowledge Databases Related to Nuclear Receptors and Proteases