New Opportunity for Discovery of Highly Differentiated Therapeutics for Alzheimer’s and Parkinson’s

Launch of novel, high throughput in vitro platform will help researchers find molecules that can prevent prion-like spreading of neurodegenerative disease associated peptides

23 Oct 2018
Finn Price
Administrator / Office Personnel

Product news

Cellectricon AB, a collaborative research organization dedicated to advancing drug discovery and research in the areas of chronic pain and CNS diseases, has announced the launch of a novel assay platform for in vitro neurodegenerative disease research. The platform, based on a patent-pending microfluidics technology, has been developed over the past two years in collaboration with a leading pharmaceutical company.

“The propagation of neurodegenerative disease associated peptides (NDAPs), such as tau and alpha-synuclein, within the brain is considered to be one of the major pathological mechanisms in progressive neurodegenerative diseases such as Alzheimer’s and Parkinson’s disease”, said Dr. Sebastian Illes, Director of CNS Research at Cellectricon. “With our new platform, we can model these neuropathological processes and we have the capacity and robustness to allow screening and profiling of larger compound sets in the search for molecules preventing prion-like spreading of NDAPs in neuronal circuits. We believe this will provide many new opportunities for the development of highly differentiated therapeutics for several neurodegenerative diseases.”

Cellectricon has successfully supported pharmaceutical companies and academic institutions for over five years with assay development, screening and preclinical compound validation for their pain and CNS disease projects. With the launch of its new assay platform, Cellectricon has significantly expanded the research opportunities available to customers working on progressive neurodegenerative diseases.

“We are extremely pleased to add this assay platform to our portfolio as it enables us to extend our services offering to encompass neurodegenerative disease research”, said Dr Mattias Karlsson, Cellectricon’s CEO. “With our new and patent-pending assay platform, we can create highly relevant, complex disease models and innovative assays for functional and morphological screening, and we are looking forward to discussing the new research possibilities that it opens up with delegates at Neuroscience in San Diego.”

To find out more, visit the Cellectricon booth #1331 at Neuroscience 2018, San Diego, CA, USA (3-7 November). Cellectricon is also presenting several posters at Neuroscience, and full details of our poster presentations can be found at: https://cellectricon.com/neuroscience-2018/

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Cell-Based AssaysCell-based assays are used to monitor the presence, quantity and activities of a desired cellular analyte including drug molecules or biomarkers. This can reveal information on cell health (apoptosis, cytotoxicity, viability and proliferation assays), cell metabolism, cell migration and cell signaling mechanisms. Find the best cell-based assay products, kits and equipment with our peer reviewed product directory: compare products, check customer reviews and receiving pricing direct from manufacturers.NeuroscienceNeuroscience research investigates the neurological mechanisms underlying behavior, neurodegenerative diseases, and other brain conditions. Learn about the innovative technologies for bioimaging, electrophysiology, cell culture, chromatography and other techniques used in this field.NeurobiologyNeurobiology studies the biology of the nervous system, including the structure and function of neurons, glial cells, and their interactions. It is a key field in understanding neurological disorders such as Alzheimer�s, Parkinson�s, and schizophrenia. Research in neurobiology is essential for developing therapies for these conditions. Browse our peer-reviewed product directory to find the best neurobiology research tools, compare products, check reviews, and get pricing directly from manufacturers.Alzheimers ResearchAlzheimer�s disease is a neurodegenerative condition characterized by progressive memory loss and cognitive decline. Research focuses on understanding the molecular and cellular mechanisms of the disease, as well as developing effective treatments and diagnostic tools. Browse our peer-reviewed product directory to find the best Alzheimer�s research products, compare options, check reviews, and get pricing directly from manufacturers.Parkinsons DiseaseNeurodegenerationNeurodegeneration refers to the progressive deterioration of the structure and function of the nervous system, often seen in diseases like Alzheimer's and Parkinson's. Research focuses on early detection and potential therapies. Explore neurodegeneration research tools in our peer-reviewed product directory; compare products, check reviews, and get pricing directly from manufacturers.
New Opportunity for Discovery of Highly Differentiated Therapeutics for Alzheimer’s and Parkinson’s