New Nanosep centrifugal device offers high binding capacity for DNA and RNA purification

12 Mar 2020
Diane Li
Assistant Editor

Product news

Pall Corporation, a global leader in filtration, separation and purification, has introduced the versatile Nucleic Acid Binding (NAB) device for applications requiring highly efficient nucleic acid isolation. The NAB Nanosep® device is said to provide increased binding capacity through its innovative dual-layer, silica-based quartz glass fiber membrane.

Using the multipurpose NAB Nanosep device, researchers can purify plasmid DNA, genomic DNA, or total RNA from a variety of starting materials. The centrifugal device can recover from 10,000 to 50 base pairs, allowing users to analyze the widest range of nucleic acid fragments in a single spin device.

The NAB Nanosep device offers flexibility and rapid processing, without sacrificing yield or quality of the nucleic acids. The device’s double-layer membrane can isolate nucleic acids with yields high enough to allow multiple downstream applications, saving time and money by eliminating the need to process additional samples. Ultrasonically welded seals prevent bypass contamination or seal failure. The device fits standard centrifuge rotors that accept 1.5 mL tubes.

The NAB Nanosep device is ideal for applications in the following workflows:

  • Purified plasmid DNA: restriction digest, cloning, and Sanger sequencing
  • Purified genomic DNA: qPCR and next-generation sequencing
  • Purified total RNA: RT-PCR and cDNA library construction

Do you use Pall Corporation products in your lab? Write a review today for your chance to win a $400 Amazon gift card>>

Macrosep® Advance Centrifugal Devices

Pall Life Sciences - Laboratory, Food, Beverage

Quickly concentrate up to 20 mL of biological sample Pall Life Sciences Macrosep Advance Centrifugal Devices Features of the Microsep Advance Centrifugal Devices:  •  Rapidly concentrates 20 mL sample volumes to 0.5 mL.   •  Provides high recoveries, typically > 90%.   •  Low protein-binding Omega membrane and polypropylene housing minimize losses due to non-specific binding.   •  Versatile Omega membrane is available in a variety of MWCOs.   •  Built-in deadstop prevents spinning to dryness.   •  Color-coded for easy identificationApplications of the Microsep Advance Centrifugal Devices: Ultrafiltration   •  Concentrate and desalt proteins.   •  Exchange buffer or remove salt of chromatography eluates and gradient fractions.  •  Recover proteins or other molecules from cell culture supernatants.  Microfiltration   •  Remove particulate from aqueous solutions and clinical samples.

(2)

Nanosep® & Nanosep MF Centrifugal Devices

Pall Life Sciences - Laboratory, Food, Beverage

Simple, reliable concentrating and desalting of 50 to 500 µL samples. Ensures rapid processing of samples. Typical recoveries are greater than 90%. Available with low protein binding Omega™, Bio-Inert®, and GHP membranes. A wide range of MWCOs, color-coded for easy identification. Constructed of low-binding polypropylene. Ultrasonically welded seals prevent bypass or seal failure. Fits standard centrifuge rotors that accept 1.5 mL tubes.

(0)

Links

Tags

DNA / RNA Extraction and PurificationPurified DNA and RNA are required for numerous downstream molecular biology applications. Consequently, the importance of high-quality DNA/RNA extraction and purification equipment cannot be underestimated. Many purification kits are available and are typically optimized for nucleic acid type and source, including plasmid DNA, genomic DNA, mRNA, RNA and viral nucleic acid purification kits. Automated extraction and purification of nucleic acids can be implemented with magnetic bead separator instruments or high-throughput purification workstations. Find the best DNA/RNA extraction and purification equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.PurificationPurification techniques are essential for isolating compounds of interest from complex mixtures, such as proteins, nucleic acids, and chemicals. These techniques are critical in biochemistry, drug development, and environmental studies. Explore purification systems in our peer-reviewed product directory; compare products, check reviews, and get pricing directly from manufacturers.qPCRQuantitative PCR (qPCR) is a molecular biology technique used to amplify and measure the amount of a specific DNA or RNA target. It plays a crucial role in gene expression analysis, pathogen detection, and quantifying DNA or RNA in various applications. Real-time PCR provides precise, quantitative results and is widely used in research, diagnostics, and clinical studies. Browse our peer-reviewed product directory to find the best qPCR solutions; compare products, check reviews, and get pricing directly from manufacturers.Multi-Sample FiltrationReal-Time PCRReal-time PCR (RT-PCR) is a technique used to amplify and simultaneously quantify nucleic acids in real time. It is a key tool in gene expression analysis, pathogen detection, and diagnostics. RT-PCR allows for the detection of specific RNA or DNA sequences with high sensitivity and specificity. Browse our peer-reviewed product directory to find the best Real-Time PCR systems; compare products, check reviews, and get pricing directly from manufacturers.Centrifuge
New Nanosep centrifugal device offers high binding capacity for DNA and RNA purification