New Microwave Synthesis System for Low-Temperature Chemistries

19 Jun 2006

Product news

Experience the benefits of increased speed and greater yields, while performing low to room temperature chemistries!

Discover® CoolMate™ is the first microwave system designed to perform sub-ambient temperature chemistries including the formation of carbanions and other highly reactive intermediates, as well as carbohydrate chemistry, easily and controllably.

CoolMate is the ideal solution for affecting stereochemical outcomes. With the addition of the CoolMate module, the Discover line of Focused™ Microwave Synthesis instruments now extends the use of
microwave energy to cover the full spectrum of synthetic chemistry.

The system also allows the safe use of highly reactive species, which would normally be excluded when using a microwave system. The system's proprietary, jacketed, low-temperature vessel and cooling technology keep the bulk temperature of the reactants low, preventing thermal degradation of the product while microwave energy drives the reaction kinetically. Measurement of the actual temperature is accomplished with an in situ fiber-optic probe placed directly into the reaction mixture to insure fast, accurate, and convenient reaction feedback control.

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Medicinal ChemistryMedicinal chemistry is a broad discipline encompassing the design, identification, synthesis and development of chemicals in drug discovery. It includes a number of techniques covering structural biology, synthetic chemistry and molecular biology. Technologies used in medicinal chemistry include ADME, lab-on-a-chip, high content screening and assay assembly.Process ChemistryProcess chemistry is an important stage of drug development for scaling-up drug production or chemical synthesis reactions. It is useful for optimizing economical and efficient drug production. Process chemistry uses reactors and pump systems as well as reagents, standards and buffers.Thermal Analysis EquipmentThermal analysis equipment is used for measuring heat flow, weight loss, dimension changes or thermomechanical properties and is important for analyzing a material’s performance and stability. Thermal analysis equipment includes differential scanning calorimeters (DSC), thermogravimetric analyzers (TGA), thermomechanical analyzers (TMA), dilatometers, thermometers, vapor sorption analyzers, boiling and melting point apparatus. Thermal analyzers can reveal properties such as melting, crystallization and glass transitions or other processes such as oxidation, decomposition, volatilization, as well as coefficients of thermal expansion and modulus. Find the best thermal analysis equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.
New Microwave Synthesis System for Low-Temperature Chemistries