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New Legionella pneumophila Monoclonal Antibodies

25 Jan 2011
Sarah Sarah
Marketing / Sales

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ViroStat has released two new monoclonal antibodies that react with the LPS of all serogroup 1 strains tested (11 strains). These antibodies can form a pair for the detection of SG1 LPS in various sources.

Legionella pneumophila is a gram negative organism found in the natural environment. It can infect man setting up an infection of the pulmonary alveolar macrophages. This condition has also been termed Legionnaire’s disease. Though there are 64 serogroups of Legionella, 70-90% of cases of pneumonia are caused by serogroup 1 of Legionella pneumophila.

ViroStat has released two new monoclonal antibodies that react with the LPS of all serogroup 1 strains tested (11 strains). These antibodies can form a pair for the detection of SG1 LPS in various sources.

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AntibodiesAntibodies are used in techniques such as confocal and fluorescence microscopy, flow cytometry, ELISA, ELISPOT, immunohistochemistry, western blotting and immunopreciptation. Select specific antigen reactivity, high specific affinity, low non-specific binding, monoclonal or polyclonal, primary or secondary antibodies and associated conjugates such as an enzyme or dye for visualization.Assay AssemblyAssay Assembly is technique used in drug discovery to develop assays to test the cytotoxicity, genotoxicity, or other activities of a compound on a cell. Assay assembly requires chip assembly, a delivery system and a detection and analysis method. Beneficial features of assay kits or automated systems include high-throughput, high speed and sensitivity and low signal to noise ratio.Process ChemistryProcess chemistry is an important stage of drug development for scaling-up drug production or chemical synthesis reactions. It is useful for optimizing economical and efficient drug production. Process chemistry uses reactors and pump systems as well as reagents, standards and buffers.Biopharmaceutical AdvancesBiopharmaceutical advances follow the development of pharmaceuticals derived from biotechnology, also known as biotechnology medicines. Biopharmaceuticals may be produced from cell lines, plants, or microbial cells. Important considerations of biopharmaceutical use include application, cost, production process and purification.Clinical TrialsClinical Trials, an essential part of drug discovery process, assess the safety and effectiveness of a new medication or device in the pharmaceutical industry. Clinical Trials are a phased process (Phase 0, Phase I, Phase II, Phase III and Phase IV) which begins after initial preclinical testing.

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New Legionella pneumophila Monoclonal Antibodies