New Kit Enables Covalent Conjugation of Antibodies and Proteins to Magnetic Particles

22 Feb 2017
Mia Harley
Biochemist

Product news

Innova Biosciences (Innova), a specialist provider of bioconjugation products and services, announced the launch of its Magnetic Conjugation Kit, the newest addition to the company’s range of particle conjugation technologies.

The new kit allows researchers to covalently conjugate antibodies and proteins to 0.5µm magnetic particles without the need for extensive optimization of the conjugation reaction, thereby saving precious antibody or protein. The Magnetic Conjugation Kit is ideal for use in immunoprecipitation experiments, as covalent attachment provides a more stable alternative to non-covalent antibody attachments using traditional Protein A or protein G resin.

The specially treated iron oxide magnetic particles offer an ideal balance between high surface area and fast separation, providing a binding capacity that is twice that of leading competitors, allowing high sensitivity to be achieved with less material and minimizing the risk of non-specific binding.

Nick Gee, CEO and CSO at Innova Biosciences, commented: “This new kit is the second product to be added to Innova’s particles range in 2017, following the launch of the Europium conjugation kit in January. We are constantly looking to develop new innovations to make scientists’ lives easier, and will be launching an additional related product later in the year.”

Innova Biosciences’ conjugation technologies include Lightning-Link® for antibody & protein labeling, InnovaCoat® GOLD nanoparticles and Latex beads for lateral flow, and Thunder-Link® for oligonucleotide conjugation.

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AntibodiesAntibodies are used in techniques such as confocal and fluorescence microscopy, flow cytometry, ELISA, ELISPOT, immunohistochemistry, western blotting and immunopreciptation. Select specific antigen reactivity, high specific affinity, low non-specific binding, monoclonal or polyclonal, primary or secondary antibodies and associated conjugates such as an enzyme or dye for visualization.Protein PurificationProtein purification is a vital step in drug discovery, therapeutics, biotech and life science research. The purification process typically involves subcellular or membrane protein extraction with cell lysis kits, separation of proteins from cell debris by filtration or spin columns, and the isolation of proteins of interest from other proteins and impurities with affinity purification (including fusion protein tags and antibody binding proteins A, G and L), immunoprecipitation or chromatographic methods, such as ion exchange, size exclusion and immobilized metal affinity chromatography. All purification methods come in multiple formats for your laboratory needs, including agarose or magnetic beads, resins, columns and filter plates. Find the best protein purification equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.ConjugationMagnetic BeadsImmunoprecipitation
New Kit Enables Covalent Conjugation of Antibodies and Proteins to Magnetic Particles