New, Improved Cytogenetics Arrays from OGT

12 Nov 2008

Product news

Oxford Gene Technology (OGT), the pioneer of microarray-based technologies, has launched the latest versions of its CytoSure™ family of high resolution oligonucleotide arrays, offering even more coverage than before for cytogenetic syndromes and accurate whole genome aberration detection. The Syndrome Plus v2 and Chromosome X High Density arrays have been developed in close collaboration with leading cytogeneticists for a complete, cost-effective array solution.

The CytoSure Syndrome Plus v2 array covers over 200 known cytogenetic syndrome regions, including 410 genes associated with autism, mental retardation, heart and eye diseases, with one probe every 3 kb. The array also offers extensive coverage of the whole genome, including subtelomeric regions and recombinant hotspots, with one probe every 40 kb. The Chromosome X High Density array has a probe density of one probe every 2 kb to target genes on the X chromosome, including exons, miRNAs, rRNAs and snRNAs. Both arrays are available in 2x105k format.

Also available is analysis software that allows easier interpretation of results with data exchange for comprehensive, state-of-the-art cytogenetic profiling.

Spencer Howell, Director of Cytogenetics at OGT said: "I am delighted to announce the release of the second generation of CytoSure oligonucleotide arrays from OGT. The newly designed arrays, along with our expanding 'Complete Solution' approach, further underlines our commitment to provide aCGH analysis in cytogenetics laboratories worldwide."

OGT offers total support from sample to result, as well as comprehensive training to users of CytoSure arrays.

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Genome AnalysisGenomics, the study of genomes, includes functional genomics, evolutionary genomics and comparative genomics. There are many genomic technologies such as DNA sequencing of whole genomes, computational biology and bioinformatics. DNA and nucleic acids must be isolated and concentrated from cells for analysis with kits, automated analyzers and software. Other useful technologies for studying genomics include PCR, microarrays and electrophoresis.OligonucleotidesOligonucleotides are small nucleic acid polymers, usually less than 20 bases in length. Oligonucleotides can be made via enzymatic cleavage or more commonly by chemical synthesis with polymerases. Their use includes FISH, southern blots, microarrays and as primers in PCR. High fidelity synthesis kits and detection systems are available for easy production and detection, respectively.Microarray AnalysisMicroarrays, also known as biochips, are used for the detection and analysis of multiple genes, proteins, antibodies, or biomarkers on a single microchip. This can reveal information on protein or gene expression, single nucleotide polymorphism (SNP), copy number variation (CNV), epigenetics and patient health in clinical diagnostic tests. Discover a range of microarray scanners and prefabricated antibody, protein, RNA and DNA microarrays for your analysis or consider creating your own custom microarrays with a microarray printer. Find the best microarray products in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Clinical TrialsClinical Trials, an essential part of drug discovery process, assess the safety and effectiveness of a new medication or device in the pharmaceutical industry. Clinical Trials are a phased process (Phase 0, Phase I, Phase II, Phase III and Phase IV) which begins after initial preclinical testing.Clinical GeneticsMolecular Genetics covers the analysis of hereditary genetic disease and chromosomal abnormalities. Genetics can be analysed using DNA, RNA, and protein microarrays, PCR, RT PCR and DNA sequencing. Genetic equipment includes genetic workstations, thermal cyclers, cooling blocks and electrophoresis products. Diagnostic kits are used for DNA / RNA extraction and purification.