SelectScience
Join Free
Accelerating Science
NewsSeparations

New Imaging detection technology platform set to revolutionise UV-Vis absorbance

Paraytec Ltd
6 Feb 2007

Product news

Paraytec (York, UK) has chosen Pittcon 2007 (Booth 514) for the public launch of its ActiPix® D-100 miniature UV imaging area detector - the world's first miniature multiplexed capillary UV area detector.

Using a capillary, as combined sample vessel and optical element, the patented ActiPix® D-100 detector provides inherent spatial separation of sample and reference beams - the result - a unique self-referencing system in a miniature format. Allowing minute (picolitre to nanlitre) volumes to be measured with high sensitivity, without sacrificing spatial resolution, the ActiPix D-100 is an ideal detector for capillary LC and CE systems. Using an active pixel area sensor to capture measurements imaging of single or multiple capillaries is readily achieved on a single sensor, unlike current commercial UV detectors. Simultaneous measurement of multiple capillaries allows extremely high throughput of samples on the ActiPix D100. Highly sensitive and linear over five orders of magnitude dynamic range, applications for the ActiPix D-100 include monitoring nanoscale biocatalytic reactions, measuring molecular size of both small molecules and biomolecules, coupling with LC or CE-MS.

Dr Mebs Surve (Business Development Manager) commented ' Our products utilise leading edge patented technology to extend the use of UV-Vis absorbance detection to a range of new biological and pharmaceutical applications. Using capillaries as sample vessels, we are able to characterise tiny sample volumes with exceptional sensitivity over a wide dynamic range. Combined with our use of active pixel area sensors alongside real-time processing software, results become not just numbers, but incredibly powerful real-time images'.

Paraytec is a scientific instrument company based in York, UK, designing, developing and manufacturing miniature UV-Visible absorbance detectors. Paraytec was established in January 2005 as a spin-out from the University of York Chemistry Department. Paraytec's founders have developed and patented an advanced detection method for UV-Vis absorbance measurement, using capillaries in conjunction with sophisticated optics and active pixel area sensors. The result is a powerful new imaging detection technology platform, which is set to revolutionise UV-Vis absorbance.

For further information please visit Pittcon Booth 514 or contact Paraytec Ltd.

Links

Paraytec LtdCompany website

Tags

Capillary ElectrophoresisCapillary electrophoresis (CE) is used to separate molecules based on charge, size and hydrophobicity. Pressure, voltage or a vacuum is used to introduce the sample to fused silica capillaries. Fluorescence, UV/Vis, UV or diode array detectors are used to visualize components. Types of CE systems include capillary electrochromatography (CEC), capillary zone electrophoresis and capillary gel electrophoresis. Find the best capillary electrophoresis equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.UV-Visible SpectroscopyUltraviolet-visible (UV-Vis) spectrophotometers are used to measure the interaction of UV and visible light with a sample, including transmission, reflectance & absorbance. The two major instrument classes are single-beam or double-beam spectrophotometers. More specialized equipment includes colorimeters, spectroradiometers and refractometers. Portable and microvolume spectrophotometers are also available. For the modular spectroscopy lab, explore a range of light sources for combination with a spectrograph/spectrometer and optics. Find the best UV-Vis spectroscopy products in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.ProteomicsProteomics is the systemic bioinformatics study of proteins and amino acids, including their structure, size, function and identification. Tools used in proteomics include chromatography, blotting and gels, protein arrays, mass spectrometry and ELISA and associated analysis software. Analyzers and proteomic systems should be sensitive, high resolution, fast and may be automated for high-throughput.NanoLCNano LC is a nano scale liquid chromatography technique typically used for proteomic applications. The nano refers to the very low flow rate of the mobile phase in the system. The advantage of nanoLC is its high sensitivity. Often the system is integrated with a mass spectrometer in nano LC-MS or nano LC-MS/MS. When using nanoLC equipment consider column choice, software and accurate and precise flow rate control.Process ChemistryProcess chemistry is an important stage of drug development for scaling-up drug production or chemical synthesis reactions. It is useful for optimizing economical and efficient drug production. Process chemistry uses reactors and pump systems as well as reagents, standards and buffers.Cell-Based AssaysCell-based assays are used to monitor the presence, quantity and activities of a desired cellular analyte including drug molecules or biomarkers. This can reveal information on cell health (apoptosis, cytotoxicity, viability and proliferation assays), cell metabolism, cell migration and cell signaling mechanisms. Find the best cell-based assay products, kits and equipment with our peer reviewed product directory: compare products, check customer reviews and receiving pricing direct from manufacturers.Biopharmaceutical AdvancesBiopharmaceutical advances follow the development of pharmaceuticals derived from biotechnology, also known as biotechnology medicines. Biopharmaceuticals may be produced from cell lines, plants, or microbial cells. Important considerations of biopharmaceutical use include application, cost, production process and purification.

Related articles

New Imaging detection technology platform set to revolutionise UV-Vis absorbance