New Gilson LC/MS Purification System

2 Jul 2012

Product news

Gilson, Inc has introduced the latest in mass spectrometry technology to the industry leading purification platforms. Developed for Preparative HPLC, the Gilson LC/MS Purification System combines best-in-class mass spectrometry with the most reliable liquid handling, injection and fraction collection platforms on the market today.

Gilson has taken the Trilution LC platform, a software package specifically designed by Gilson for preparative purification, and integrated control of the PerkinElmer FLEXAR SQ 300 MS Detector to trigger mass-based fraction collection. Conditional logic collection of Trilution LC allows for utilizing UV, DAD and/or ELSD and up to seven target masses with 1 to 3 adducts per target mass in SIM or SCAN with Extracted Ion modes, making the collection of fractions a quick and easy process.

“Mass-based purification no longer has to be an intimidating or difficult system to use.” Said Atika El Sayed, CEO of Gilson, Inc. “Full control of the Flexar Detector is as simple and easy to follow as any detector in the software, but provides the specificity and efficiency of mass-based purification. Most LC/MS systems use software packages that are more focused on the MS data and in-depth control of the MS, which add a high level of complexity. Our simple-to-use Trilution software package simply treats the MS detector as it does any other detector.”

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UHPLC and HPLCHigh performance liquid chromatography (HPLC) and ultra high performance liquid chromatography (UHPLC), also known as UPLC, are analytical techniques used to separate, identify and quantitate components of complex mixtures including biological samples such as proteins and lipids as well as chemical mixtures of pesticides, drugs and oils. Both techniques are liquid chromatographic methods but differ by operating pressures (HPLC < 6000 psi < UHPLC ). Components of HPLC and UHPLC systems include columns, detectors, pumps, autosamplers and column heaters. Explore a range of UHPLC and HPLC columns for your specific sample needs including reverse phase, normal phase, ion exchange, HILIC, ion exclusion and size exclusion columns. For more specialized HPLC, explore FPLC, countercurrent LC and simulated moving bed systems. Find the best UHPLC and HPLC equipment in our peer reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.LC-MSLC-MS (liquid chromatography-mass spectrometry) systems and equipment are used for separation and quantitative analysis of complex mixtures, combining liquid chromatography and mass spectrometry. Quantify proteins, contaminants, pesticides or screen for drug metabolites with a high level of sensitivity. LC-MS systems and equipment include reverse phase, normal phase and specialized columns integrated with various MS detectors such as time-of-flight (TOF), quadrupole, orbitrap or ion trap mass analyzers. LC-MS/MS instruments equipped with a qTOF or triple quadrupole analyzer give greater sensitivity and resolving power to your analysis. Find the best LC-MS equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Mass SpectrometryMass spectrometry (MS) is a powerful analytical technique used to identify and quantify molecules based on the mass-to-charge ratio of gas-phase ions. It provides detailed information about the structure, composition, and properties of compounds and is widely used across fields such as environmental monitoring, materials science, drug discovery and development, food and beverage testing, and wider chemical research. Key MS techniques include tandem mass spectrometry (MS/MS), liquid chromatography–mass spectrometry (LS-MS) and inductively coupled plasma (ICP-MS). Choosing from these wide range of techniques and technologies can be a daunting task, so keep up to date with scientific applications, performance expectations, and customer reviews here all in one place. Visit our product directory to receive quotes direct from the manufacturer.
New Gilson LC/MS Purification System