New genetic analyzer brings advanced capabilities to sanger sequencing and fragment analysis

Thermo Fisher Scientific expands Applied Biosystems portfolio with the latest generation of innovative, mid-throughput genetic analyzers

9 Feb 2022
Blake Forman
Content Creator

Product news

Capillary electrophoresis (CE), which enables Sanger sequencing and fragment analysis, is an important tool for improving clinical research and advancing scientific discovery. To further enable customers’ cutting-edge research in areas such as gene editing and infectious disease, Thermo Fisher Scientific introduced the new Applied Biosystems SeqStudio Flex Series Genetic Analyzer.

“Labs around the world rely on Applied Biosystems’ CE-based instruments for gold-standard Sanger sequencing and fragment analysis data,” said Kay Eron, vice president and general manager of capillary electrophoresis, Thermo Fisher Scientific. “As Thermo Fisher celebrates the fortieth anniversary of the Applied Biosystems brand, we will continue to invest in CE technology as a core platform in our sequencing portfolio. We designed the SeqStudio Flex Series Genetic Analyzers with our customers in mind, offering a simplified, more efficient workflow, multiple applications, and an exceptional level of accuracy to advance their research.”

Building on proven Applied Biosystems technology, the new mid-throughput genetic analyzer introduces design and technological advancements for enhanced flexibility, usability, and connectivity. The instrument has increased plate capacity and may be loaded at any time without canceling or waiting for a run to complete, improving sample throughput, walk-away capacity, and scheduling flexibility.

The system’s advanced Wi-Fi connectivity enables users to remotely set up and monitor runs, as well as to facilitate streamlined data transfer, analysis, and scientific collaboration. The SeqStudio Flex Series Genetic Analyzer is also the first CE-based instrument with remote servicing capabilities for faster issue resolution.

“The SeqStudio Flex analyzer is the most intuitive and flexible sequencer we have ever used,” said Peter Böhm, MSc, chief biomedical laboratory scientist for the department of clinical genetics at Righospitalet, a large, specialized hospital in Denmark. “Our work researching genetic diseases relies on fast turn-around times, high data quality, and easy connection to equipment specialists during troubleshooting. The SeqStudio Flex package has it all.”

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Applied Biosystems SeqStudio Genetic Analyzer

Thermo Fisher Scientific

The new Applied Biosystems SeqStudio Genetic Analyzer is a low-throughput, easy-to-use, and convenient benchtop system that delivers gold-standard Sanger sequencing technology and fragment analysis with just a simple click. It is easily used across a broad range of applications as well as by multiple users. Without complex setup, you will be ready to go in minutes.

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Capillary ElectrophoresisCapillary electrophoresis (CE) is used to separate molecules based on charge, size and hydrophobicity. Pressure, voltage or a vacuum is used to introduce the sample to fused silica capillaries. Fluorescence, UV/Vis, UV or diode array detectors are used to visualize components. Types of CE systems include capillary electrochromatography (CEC), capillary zone electrophoresis and capillary gel electrophoresis. Find the best capillary electrophoresis equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.ElectrophoresisElectrophoresis equipment is used to separate mixtures of protein, DNA or RNA, based on their electric charge, size and other physical characteristics, by passing them through a medium such as a polyacrylamide gel, an agarose gel or a capillary tube. Electrophoresis equipment includes horizontal and vertical gel electrophoresis chambers, isoelectric focusing systems, 2D electrophoresis and capillary electrophoresis instruments. Precast gels with a gradient can be used or gels can be hand cast. Samples are run alongside ladders or markers to identify the approximate size of a molecule. Separated proteins and nucleic acids in the gel can be stained or probed with fluorescent markers and then imaged and detected using gel documentation instruments, transilluminators, densitometers and scanners. Find the best electrophoresis equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Gene EditingGene editing is the precise alteration to an organism's DNA, with CRISPR being the most well-known technique. It is used in a wide range of applications, including the development of disease models and gene therapy, and crop improvement. Browse our peer-reviewed product directory to find the best gene editing solutions, compare products, check reviews, and get pricing directly from manufacturers.Infectious DiseasesInfectious diseases are caused by pathogens such as bacteria, viruses, and fungi. Effective detection, prevention, and treatment are crucial to control outbreaks and improve public health. Diagnostic tools, vaccines, and antimicrobial treatments are essential components of managing these diseases. Research into emerging pathogens and resistance patterns continues to evolve. Browse our peer-reviewed product directory to find the best diagnostic tools, prevention solutions, and treatment options; compare products, read customer reviews, and get pricing directly from manufacturers.