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New family of aroma compounds found in cannabis

SepSolve Analytical

An analytical system provided by SepSolve aided this breakthrough in cannabis research

2 Jan 2022
Dora Wells
Clinical Content Editor

Industry news

Cannabis aroma is so complex, the volatile organic compounds responsible for its characteristic ‘skunk-like’ smell have eluded researchers until now. A recently published paper describes the discovery of a new family of volatile sulfur compounds in cannabis, which were proved to be responsible for its pungent aroma, using two-dimensional gas chromatography.

The paper was co-authored by Abstrax Tech, a company that develops cannabis- and botanically-derived terpenes, and SepSolve Analytical.

The analytical system used in the study was custom-built by SepSolve and consists of a Centri® sample extraction and enrichment platform coupled with a two-dimensional gas chromatograph, BenchTOF™ mass spectrometer, flame ionization detector, and sulfur chemiluminescence detector.

The paper – Identification of new family of prenylated volatile sulfur compounds in cannabis revealed by comprehensive two-dimensional gas chromatography – demonstrates that the data acquired using this approach could lead to a full elucidation of the biosynthetic pathways and medicinal benefits of different cannabis strains.

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Oswald I, Ojeda M, Pobanz R, Koby K, Buchanan A, Del Rosso J, Guzman M and Martin T. 2021. Identification of a New Family of Prenylated Volatile Sulfur Compounds in Cannabis Revealed by Comprehensive Two-Dimensional Gas Chromatography. ACS Omega, 6(47), 31667-31676.

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Gas ChromatographyGas chromatography (GC) is an analytical technique used to separate and quantitate mixtures of small and volatile compounds. Gas chromatographs or GC systems include components such as GC columns, detectors, pumps and autosamplers. Choose from packed or capillary GC columns, flame ionization (FID), photoionization (PID) electron capture detectors and selective or non-selective detectors. Find the best gas chromatographs in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Mass SpectrometryMass spectrometry (MS) is a powerful analytical technique used to identify and quantify molecules based on the mass-to-charge ratio of gas-phase ions. It provides detailed information about the structure, composition, and properties of compounds and is widely used across fields such as environmental monitoring, materials science, drug discovery and development, food and beverage testing, and wider chemical research. Key MS techniques include tandem mass spectrometry (MS/MS), liquid chromatography–mass spectrometry (LS-MS) and inductively coupled plasma (ICP-MS). Choosing from these wide range of techniques and technologies can be a daunting task, so keep up to date with scientific applications, performance expectations, and customer reviews here all in one place. Visit our product directory to receive quotes direct from the manufacturer. GC-MS GC-MS (gas chromatography-mass spectrometry) instruments and equipment are used to separate, quantify and identify mixtures of small and volatile compounds, such as polycyclic aromatics, fatty acids and alcohols. Often used in drug detection, forensic investigation and environmental analysis for pesticides and contaminants, GC-MS is a powerful addition to your lab’s analytical capabilities. GC-MS/MS instruments equipped with a qTOF or triple quadrupole analyzers can give greater sensitivity and resolution to your analysis. Find the best GC-MS instruments and equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.SulfurCannabisGas ChromatographyGas chromatography (GC) is an analytical technique used to separate and analyze gases or volatile liquids in a sample. It is widely used in environmental testing, food safety, pharmaceuticals, and forensic science. GC is ideal for identifying and quantifying compounds that are gaseous or can be vaporized without decomposition. Browse our peer-reviewed product directory to find the best gas chromatography systems, compare products, check reviews, and get pricing directly from manufacturers.Aroma Profiling

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