New Enrichment Kit from Thermo Fisher Scientific Improves Analysis of Phosphopeptides using Mass Spectrometry

7 Jan 2011
Sarah Sarah
Marketing / Sales

Product news

Thermo Fisher Scientific announces the Thermo Scientific Pierce TiO2 Phosphopeptide Enrichment and Clean-up Kit for improving mass spectrometry analysis of phosphoproteins. The TiO2 resin in the kit provides an alternative to IMAC resins, and it enriches more phosphopeptides and preferentially enriches for monophosphorylated peptides.

When used in conjunction with the Thermo Scientific Pierce Fe-NTA IMAC Phosphopeptide Enrichment Kit, researchers can obtain a more comprehensive view of the different phosphopeptide species using mass spectrometry.

The Pierce TiO2 Enrichment and Clean-up Kit provides sufficient reagents to process 24 samples. The TiO2 Spin Tips in the kit recover up to 300 micrograms of phophopeptides, with greater than 90 percent selectivity. Clean-up of the recovered phosphopeptides is achieved with the Pierce Graphite Spin Columns included in the kit. The Pierce TiO2 Spin Tips and Pierce Graphite Spin Columns are also available separately.

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Mass SpectrometryMass spectrometry (MS) is a powerful analytical technique used to identify and quantify molecules based on the mass-to-charge ratio of gas-phase ions. It provides detailed information about the structure, composition, and properties of compounds and is widely used across fields such as environmental monitoring, materials science, drug discovery and development, food and beverage testing, and wider chemical research. Key MS techniques include tandem mass spectrometry (MS/MS), liquid chromatography–mass spectrometry (LS-MS) and inductively coupled plasma (ICP-MS). Choosing from these wide range of techniques and technologies can be a daunting task, so keep up to date with scientific applications, performance expectations, and customer reviews here all in one place. Visit our product directory to receive quotes direct from the manufacturer. ProteomicsProteomics is the systemic bioinformatics study of proteins and amino acids, including their structure, size, function and identification. Tools used in proteomics include chromatography, blotting and gels, protein arrays, mass spectrometry and ELISA and associated analysis software. Analyzers and proteomic systems should be sensitive, high resolution, fast and may be automated for high-throughput.
New Enrichment Kit from Thermo Fisher Scientific Improves Analysis of Phosphopeptides using Mass Spectrometry