New electrophoresis High Resolution Immunofixation using Hydragel kit from Sebia

8 Dec 2006

Product news

A new Hydragel kit for the HYDRASYS agarose gel electrophoresis system is now available from Sebia UK.

The High Resolution Immunofixation technique detects and identifies monoclonal proteins and Bence Jones monoclonal kappa or lambda free light chains in serum and urine to aid diagnosis and monitoring of disease. Even low concentrations of paraproteins may be significant so high sensitivity electrophoresis of urine and serum is essential for accurate diagnosis.

The new procedure uses longer application and migration times than standard methods to greatly improve the resolution in the beta and gamma zone; this can be an aid to interpreting certain samples with multiple bands such as oligoclonal patterns.

This new Hydragel kit is part of an expanding range of applications for HYDRASYS confirming its position as the leading gel electrophoresis system for clinical laboratories. A high degree of automation combined with flexible programming makes it the preferred instrument for laboratories with variable workloads.

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ElectrophoresisElectrophoresis equipment is used to separate mixtures of protein, DNA or RNA, based on their electric charge, size and other physical characteristics, by passing them through a medium such as a polyacrylamide gel, an agarose gel or a capillary tube. Electrophoresis equipment includes horizontal and vertical gel electrophoresis chambers, isoelectric focusing systems, 2D electrophoresis and capillary electrophoresis instruments. Precast gels with a gradient can be used or gels can be hand cast. Samples are run alongside ladders or markers to identify the approximate size of a molecule. Separated proteins and nucleic acids in the gel can be stained or probed with fluorescent markers and then imaged and detected using gel documentation instruments, transilluminators, densitometers and scanners. Find the best electrophoresis equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Gel Doc / Image AnalysisGel documentation (gel doc) or gel imaging systems are used for the analysis of proteins, antibodies and nucleic acid immobilized in polyacrylamide or agarose gels, membranes or microarrays. Explore a range of a gel imaging systems, densitometers, scanners, transilluminators or UV lamp + CCD cameras for your image analysis solutions. Colorimetric, fluorescent and/or radioisotopic samples can be visualized and documented for further analysis. See gel doc / Image analysis software for quantitative 1D and 2D analysis of your samples. Find the best gel doc / image analysis products in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Point-of-CarePoint-of-Care Testing (POCT) or Near Patient Testing (NPT) products are available for urine, blood and other clinical chemistry analyses. POCT includes: blood glucose testing, blood gas and electrolytes analysis, rapid coagulation testing (PT / INR), rapid cardiac markers diagnostics, drugs of abuse screening, urine strips testing, pregnancy testing, fecal occult blood analysis, food pathogens screening, hemoglobin diagnostics, infectious disease testing and cholesterol screening.
New electrophoresis High Resolution Immunofixation using Hydragel kit from Sebia