New DynaPro Plate Reader for Automated Characterization of Size, Molecular Weight and Stability of Macromolecules and Nanoparticles

23 Oct 2017
Finn Price
Administrator / Office Personnel

Product news

Wyatt Technology, a world leader in instrumentation for absolute macromolecular and nanoparticle characterization, announces the launch of its next generation, all-in-one instrument for automated characterization of size, molecular weight, aggregation and stability: the DynaPro® Plate Reader III. This latest innovation marks an entirely new level of productivity for scientists. It is now the only instrument to combine both Dynamic Light Scattering (DLS) and Static Light Scattering (SLS) in a single, fully automated platform with measurements taken directly in 96, 384 or 1536 industry-standard microwell plates.

The new DynaPro Plate Reader III can rapidly screen proteins, nanoparticles, colloids and macromolecules to determine their size, molecular weight, aggregation and stability profiles using as little as 4 μL of sample. Furthermore, the instrument can characterize both conformational and colloidal stability indicators like Tonset, Tagg, A2 and kD by simply running a temperature ramp or concentration series. Scientists can also quickly perform viscosity determinations for the viability of biopharmaceuticals and use the built-in camera to image each well for additional insight.

Discover more news about the latest microplate readers in our Lab Automation Community >>

Geofrey Wyatt, President of Wyatt Technology, said “Among our many innovations of the past few years, I’m particularly proud of the work our team has done on this instrument. We interviewed scores of our existing and potential customers to find out what they really wanted in a plate-based DLS instrument, and the DynaPro Plate Reader III is the result. This new product creates novel opportunities to advance the speed of biopharmaceutical and nanoparticle screening and development by using industry-standard, readily available well plates.”

The DynaPro Plate Reader III is one more way Wyatt Technology fulfills its mission to help ensure our customers’ success in characterizing and developing cutting-edge, life-enhancing biopharmaceuticals.

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Microplate Readers / DetectorsMicroplate readers are used to automate the detection and analysis of labeled or label-free components in microplates during assays or live-cell monitoring. Microplate readers are generally distinguished by their mode of detection. Types include absorbance, luminescence, fluorescence intensity, fluorescence polarization, TRF / FRET and multimode microplate readers. Microplate readers deliver a high throughput of samples by reading multiple wells simultaneously, with the 96-well format the most commonly used. As a result, microplate readers are often used in the drug discovery, bioassays, research and pharmaceutical industries for screening applications. Microplate loading can also be automated, with robotic microplate stackers to increase throughput. Find the best microplate readers in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.AutomationAutomation in laboratories and manufacturing processes enhances efficiency, precision, and scalability by reducing the need for manual intervention. It plays a critical role in improving productivity, minimizing human error, and accelerating workflows in fields like diagnostics, drug development, and industrial testing. Automation technologies include robotic systems, automated liquid handlers, and process control systems that streamline complex tasks and ensure consistent, reproducible results. Explore our peer-reviewed product directory to discover the best automation solutions, compare options, read user reviews, and get prices directly from manufacturers.BiopharmaceuticalsBiopharmaceuticals are proteins and other compounds (such as nucleic acids) produced by living organisms that have uses as therapeutics or for in vivo diagnostics. The most well known example of a biopharmaceutical product, and the first to be approved for therapeutic use, was recombinant human insulin.Dynamic Light ScatteringDynamic light scattering is used to measure the size distribution of particles in suspension by analyzing the way light scatters off them. It is commonly used in materials science, nanotechnology, and protein characterization. Browse our peer-reviewed product directory to find the best dynamic light scattering systems, compare products, check reviews, and get pricing directly from manufacturers.ScreeningUsing robotics, data processing and control software, liquid handling devices and sensitive detectors, screening allows a researcher to quickly conduct millions of chemical, genetic or pharmacological tests.NanoparticlesNanoparticles are between 1-100nm in size. Nanoparticles can be used for a wide variety of applications including biomedical, catalysis and electronics.