New CytoSure™ Interpret Software for Faster and Easier Translation of Oligo aCGH Data into Results

12 Oct 2010
Sarah Sarah
Marketing / Sales

Product news

This new release from Oxford Gene Technology (OGT) builds on previous software package with the addition of significant functionality such as the ‘Accelerate’ workflow, for speeding-up and streamlining the analysis and interpretation of aCGH data. Developed through consultation with users, CytoSure Interpret ensures that cytogeneticists and molecular biologists benefit from highly flexible workflows and in-depth contextual information for clearer data interpretation.

Dr. Agne Liedén from the Department of Molecular Medicine and Surgery, Karolinska Institutet commented: “I am extremely impressed with the ease-of-use and flexibility of the new CytoSure Interpret software. The main highlight for me is that I can include data from our own results, multiple annotation tracks for known CNVs from all major sources, as well as the population analysis tool.”

The CytoSure Interpret ‘Accelerate’ function enables the automation of data analysis workflows, minimising the need for user intervention and maximising the consistency and speed of data interpretation. Users are able to tailor the software to their needs, customising numerous functions including normalisation, aberration detection and report generation. Importantly, CytoSure Interpret provides comprehensive contextual input by fully integrating results with legacy data, confirmation probe information (including FISH and MLPA), as well as extensive annotation tracks covering syndromes, genes, exons, CNVs and recombination hotspots. Furthermore, these link to publicly available databases such as Decipher and the Database of Genomic Variants to provide even greater context.

James Clough, Commercial Director at OGT, stated: “The advanced functionality of CytoSure Interpret is a result of our ongoing and extremely valuable discussions with our users. We believe that CytoSure Interpret offers a step-change in the analysis and interpretation of aCGH data, enabling researchers to handle large volumes of data to move our understanding forward.”

In addition to this advanced interpretation software, the OGT CytoSure aCGH product line includes a range of high quality arrays covering single disorders through to entire syndrome spreads, as well as SciGene automation instrumentation (now distributed in Europe by OGT). As a result, OGT’s comprehensive products and services are the ideal solution for running oligo aCGH in the laboratory.

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Genome AnalysisGenomics, the study of genomes, includes functional genomics, evolutionary genomics and comparative genomics. There are many genomic technologies such as DNA sequencing of whole genomes, computational biology and bioinformatics. DNA and nucleic acids must be isolated and concentrated from cells for analysis with kits, automated analyzers and software. Other useful technologies for studying genomics include PCR, microarrays and electrophoresis.OligonucleotidesOligonucleotides are small nucleic acid polymers, usually less than 20 bases in length. Oligonucleotides can be made via enzymatic cleavage or more commonly by chemical synthesis with polymerases. Their use includes FISH, southern blots, microarrays and as primers in PCR. High fidelity synthesis kits and detection systems are available for easy production and detection, respectively.ProteomicsProteomics is the systemic bioinformatics study of proteins and amino acids, including their structure, size, function and identification. Tools used in proteomics include chromatography, blotting and gels, protein arrays, mass spectrometry and ELISA and associated analysis software. Analyzers and proteomic systems should be sensitive, high resolution, fast and may be automated for high-throughput.Data AnalysisData analysis hardware and software is available to make data processing straight-forward yet powerful. Data software can be used for math and stats, technical graphing and image analysis. In addition, software is available for specific data analysis of electrophoresis, densitometry, ELISA and DNA sequencing.Microarray AnalysisMicroarrays, also known as biochips, are used for the detection and analysis of multiple genes, proteins, antibodies, or biomarkers on a single microchip. This can reveal information on protein or gene expression, single nucleotide polymorphism (SNP), copy number variation (CNV), epigenetics and patient health in clinical diagnostic tests. Discover a range of microarray scanners and prefabricated antibody, protein, RNA and DNA microarrays for your analysis or consider creating your own custom microarrays with a microarray printer. Find the best microarray products in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.
New CytoSure™ Interpret Software for Faster and Easier Translation of Oligo aCGH Data into Results