SelectScience
Join Free
Accelerating Science
NewsLife Sciences

New Compound Libraries from BioFocus

26 Sept 2010
Sarah Sarah
Marketing / Sales

Product news

BioFocus announces two new compound libraries targeting Family C GPCR’s and protein-protein interactions. PPI01 is a new protein-protein interaction library and designed around a novel scaffold that mimics a “beta-sheet type” hydrogen bonding pattern, a key motif observed in protein-protein interactions. The new FieldFocus GPCR Library (FFG01) is designed using field- and shape-based overlays of known ligands to generate a novel library that targets the allosteric site of metabotropic glutamate receptors, a subtype of Family C GPCRs.

“These latest libraries target areas that are of specific interest to the drug discovery community” said Richard Gordon, Senior Director, Sales and Marketing BioFocus. “In the past 10 years we have expanded our range of available libraries from kinase and GPCR focused, to those targeting ion channels, nucleosides and proteases, and most recently a series targeting protein-protein interactions, providing a level of success of which we are extremely proud."

Tags

ProteomicsProteomics is the systemic bioinformatics study of proteins and amino acids, including their structure, size, function and identification. Tools used in proteomics include chromatography, blotting and gels, protein arrays, mass spectrometry and ELISA and associated analysis software. Analyzers and proteomic systems should be sensitive, high resolution, fast and may be automated for high-throughput.Compound LibrariesCompound libraries, or chemical libraries, are used in drug discovery for the identification of potential therapeutics compounds. Used in conjunction with high-throughput screening, the libraries of stored compounds are often generated for specific purposes as a drug target or disease model. Cheminformatics are commonly used when designing a compound library and software can be used to analyze the screening process.  Protein PurificationProtein purification is a vital step in drug discovery, therapeutics, biotech and life science research. The purification process typically involves subcellular or membrane protein extraction with cell lysis kits, separation of proteins from cell debris by filtration or spin columns, and the isolation of proteins of interest from other proteins and impurities with affinity purification (including fusion protein tags and antibody binding proteins A, G and L), immunoprecipitation or chromatographic methods, such as ion exchange, size exclusion and immobilized metal affinity chromatography. All purification methods come in multiple formats for your laboratory needs, including agarose or magnetic beads, resins, columns and filter plates. Find the best protein purification equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.

Related articles

New Compound Libraries from BioFocus