New Columns from Dionex Address Regulatory Requirements for Biopharmaceutical Characterization

30 Jun 2010
Sarah Sarah
Marketing / Sales

Product news

The new MAbPac™ SCX-10 column from Dionex Corporation is specifically designed for high-resolution, high-efficiency analysis of monoclonal antibodies and associated variants. This new column’s unique nonporous pellicular resin provides unmatched high resolving power, permitting the separation of monoclonal antibody variants that differ by as little as one charged residue. Hydrophobic interactions with the resin are eliminated for very efficient peaks. The column is designed to address the regulatory requirements for biopharmaceutical characterization.

The MAbPac SCX-10 a strong cation exchange column is complimentary to the industry-leading Dionex ProPac® WCX-10 column for monoclonal antibody variant analysis offering an alternative selectivity and will provide higher resolution and efficiency for variant analysis of some monoclonal antibody samples then the ProPac WCX-10 column. The new column is ideal for the high resolution, high efficiency analysis of monoclonal antibodies and associated variants and is available in 4 x 250 mm format.

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Ion ChromatographyIon chromatography, also known as ion exchange chromatography, is a high-performance liquid chromatographic technique used for the separation and identification of ions or polar molecules in a sample, including proteins, nucleotides and amino acids. Equipment includes ion exchange columns, ion exclusion columns, ion chromatography systems, pumps, and detectors. Find the best ion chromatography equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.AntibodiesAntibodies are used in techniques such as confocal and fluorescence microscopy, flow cytometry, ELISA, ELISPOT, immunohistochemistry, western blotting and immunopreciptation. Select specific antigen reactivity, high specific affinity, low non-specific binding, monoclonal or polyclonal, primary or secondary antibodies and associated conjugates such as an enzyme or dye for visualization.Biopharmaceutical AdvancesBiopharmaceutical advances follow the development of pharmaceuticals derived from biotechnology, also known as biotechnology medicines. Biopharmaceuticals may be produced from cell lines, plants, or microbial cells. Important considerations of biopharmaceutical use include application, cost, production process and purification.