New Columns Deliver Enhanced Separation and Peak Shape of Basic Compounds Under Neutral and Acidic pH Conditions

18 Oct 2010
Sarah Sarah
Marketing / Sales

Product news

Phenomenex adds two new phases to Kinetex® Core-Shell HPLC column line. Kinetex XB-C18 and Kinetex C8 bring the advantages of ultra-high liquid chromatography performance (UHPLC) within standard HPLC operating pressures to a growing list of applications.

The new Kinetex XB-C18 provides a unique selectivity, incorporating two iso-butyl side chains at the base of the C18 ligand to reduce secondary interactions with residual silanols. In comparison studies with other C18 columns, this new Kinetex phase has produced differences in peak elution order and improved separation of co-eluting compounds.

The new Kinetex C8 phase meets the United States Pharmacopeia (USP) specifications for Classification Code L7, enabling laboratories using L7 columns to realize the benefits of Kinetex core-shell technology while staying compliant with USP-allowable adjustments.

“We introduced our revolutionary Kinetex core-shell technology one year ago, and the market response and adoption rate have exceeded our expectations,” comments Jeremy Bierman, brand manager for Phenomenex. “We’re pleased to add these two new phases to the three we initially offered. Our product development team will continue to bring even more core-shell resources to the chromatography field.”

The new Kinetex core-shell columns are available in two particle sizes – 2.6- and 1.7- micron – and in variety of column dimensions.

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UHPLC and HPLCHigh performance liquid chromatography (HPLC) and ultra high performance liquid chromatography (UHPLC), also known as UPLC, are analytical techniques used to separate, identify and quantitate components of complex mixtures including biological samples such as proteins and lipids as well as chemical mixtures of pesticides, drugs and oils. Both techniques are liquid chromatographic methods but differ by operating pressures (HPLC < 6000 psi < UHPLC ). Components of HPLC and UHPLC systems include columns, detectors, pumps, autosamplers and column heaters. Explore a range of UHPLC and HPLC columns for your specific sample needs including reverse phase, normal phase, ion exchange, HILIC, ion exclusion and size exclusion columns. For more specialized HPLC, explore FPLC, countercurrent LC and simulated moving bed systems. Find the best UHPLC and HPLC equipment in our peer reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.
New Columns Deliver Enhanced Separation and Peak Shape of Basic Compounds Under Neutral and Acidic pH Conditions