New CELLSTAR Culture Vessels With Cell-Repellent Surface

Greiner Bio-One, a leading technology partner for the diagnostic and pharmaceutical industry, will be showcasing the new CELLSTAR cell culture vessels with a cell-repellent surface at the annual meeting of the "American Society for Cell Biology", ASCB. This surface has been spe-cifically developed to effectively prevent the attachment of semi-adherent and adherent cell lines. The cell-repellent surface is ideal for cultivating spheroids and embryoid bodies.

The cell-repellent effect of the new surface is achieved through a stable chemical modification of the plastic. Unlike the conventional CELLSTAR suspension surface, the surface modification even pre-vents attachment of semi-adherent and adherent cell lines such as macrophages.

The cell-repellent surface inhibits very effectively interaction between the cell culture vessel and cells. Therefore, it supports in particular the formation of spheroids, which are playing an increasingly im-portant role as 3D models in pharmaceutical research. Additionally, the cell-repellent surface supports the formation of "embryoid bodies" – non-adherent cell clusters that occupy a key position in cultivat-ing stem cells.

The new CELLSTAR cell culture vessels with cell-repellent surface are free of detectable DNases, RNases and human DNA. They contain no detectable endotoxins or cytotoxic substances, are sterile and have a shelf life of two years. Initially, Greiner Bio-One will offer the cell-repellent surface for 96 well microplates with F or U bottom, 6 well multiwell plates and the 100 mm cell culture dish.

Cell culture vessels with a cell-resistant surface are part of the CELLSTAR® product line from Greiner Bio-One.

Greiner Bio-One at the annual meeting of the American Society for Cell Biology, 15 - 19 December 2012, San Francisco, CA, USA, Stand No. 1131.