New antibody detection platform offers accelerated multiplex detection of antibodies against pathogens or autoantibodies against biomarkers

Introduced at AACC, the VeraPrep Antibody Detection Kit enables researchers to measure antibodies against any antigen of interest in serum, plasma or saliva

30 Sept 2021
Ellen Simms
Product and Reviews Editor

Product news

Veravas, Inc., an early-stage diagnostics company, has announced the development of its VeraPrep™ Antibody Detection Kit, a new development platform that provides scientists with a state-of-the-art research tool to easily and quickly develop new tests to multiplex detect and measure immunoglobulins against new and emerging pathogens as well as autoantibodies against cardiac, neurologic, and cancer biomarkers. The ability to preanalytically remove sample interferences from a larger sample and subsequently concentrate makes it possible to detect antibodies in low abundance from serum, plasma, saliva, or saline oral rinse samples.

The patented VeraPrep process uses proprietary magnetic beads with unique, low nonspecific binding properties that isolate and remove interfering antibodies in the sample. With a cleaned sample, targeted IgA, IgG and IgM immunoglobulins can be concentrated, captured and multiplex measured in a single test using the kit’s proprietary reagent beads that are coated with the researcher’s antigen of interest.

“The VeraPrep antibody detection technology offers a first of its kind platform that addresses unmet clinical needs,” said John Forrest, Co-founder and Chief Executive Officer of Veravas. “There are numerous applications for this technology that we believe will support research and simplify and accelerate the development of a host of new serology and autoantibody tests in areas such as cardiology, neurology, oncology, immunology and drug development.”

The VeraPrep Antibody Detection Kit is intended for Research Use Only (RUO) and includes all reagents required to support researchers’ test developments for up to 50 samples, in configurations for Serum/Plasma or Saliva/Saline Oral Rinse.

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AntibodiesAntibodies are used in techniques such as confocal and fluorescence microscopy, flow cytometry, ELISA, ELISPOT, immunohistochemistry, western blotting and immunopreciptation. Select specific antigen reactivity, high specific affinity, low non-specific binding, monoclonal or polyclonal, primary or secondary antibodies and associated conjugates such as an enzyme or dye for visualization.ImmunologyImmunological techniques measure and characterize immune responses. Immunology kits and analysis systems often use techniques such as ELISA, radioimmunoassay (RIA) and immunodiffusion assays, Immunohistochemistry, and flow cytometry. Immunologists use equipment such as flow Cytometers, plate readers, plate washers and fluorescent microscopes.BiomarkersBiomarkers are biological markers which can be measured and evaluated to indicate a biological state. The use of biomarkers in research and diagnosis can indicate a normal or disease state or drug response of cells / tissues. Biomarkers include genetic markers, cell surface markers such as antigens, antibodies or receptors and secreted molecules such as cytokines. An assay system is required for identification of biomarkers. :Clinical ChemistryBiochemistry (or clinical chemistry) involves the analysis of bodily fluids using chemical tests. Techniques used include HPLC, chromatography, spectroscopy, mass spectrometry, immunochemical, electrophoresis, turbidometric / spectrophotometric assay, MRI and ISE analysis. Tests are often carried out on plasma or serum but urine (urinalysis) and fecal specimens are also processed.Antibodies
New antibody detection platform offers accelerated multiplex detection of antibodies against pathogens or autoantibodies against biomarkers