New 1.3-Micron Kinetex Core-Shell Media Delivers Superior UHPLC Performance

15 Jan 2013

Product news

Phenomenex Inc., a global leader in the research and manufacture of advanced technologies for the separation sciences, announces the addition of 1.3-micron UHPLC columns to its Kinetex core-shell product line. With the smallest diameter in the Kinetex family, the 1.3-micron is the most efficient particle on the market, delivering measurably better performance than conventional fully porous media on UHPLC equipment. The Kinetex core-shell family now includes four particle sizes, from 1.3- to 5-micron, providing separation solutions for virtually every chromatographic application and easy method transferability from UHPLC to HPLC to preparative-scale LC.

“The Kinetex product line spans our customers’ needs, from sub-2-micron UHPLC to small-scale purification, enabling everyone to take advantage of the performance and productivity gains that core-shell technology can deliver,” comments Simon Lomas, brand manager for Phenomenex.

With efficiency levels over 400,000 plates per meter, the Kinetex 1.3-micron represents a dramatic advancement in LC media technology. UHPLC users can now reach previously unavailable levels of sensitivity and performance, with the added benefit of easy method transferability and scalability to any of the three other Kinetex particle sizes. While fully porous sub-2-micron columns exhibit significant band broadening due to frictional heating as flow rate increases, the Kinetex particle morphology and packing technology help to reduce these and other effects to ensure high resolution and sensitivity over an extended linear velocity.

Phenomenex core-shell products meet researchers’ need to improve results and increase productivity with their current instrumentation. By delivering significant improvements in speed and separation power over traditional fully porous columns, Kinetex columns enable chromatographers to get superior results on any LC or UHPLC platform, along with potential reductions in solvent usage.

Phenomenex is a global technology leader committed to developing novel analytical chemistry solutions that solve the separation and purification challenges of researchers in industrial, clinical research, government and academic laboratories. From drug discovery and pharmaceutical development to food safety and environmental analysis, Phenomenex chromatography solutions accelerate science and help researchers improve global health and well-being.

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UHPLC and HPLCHigh performance liquid chromatography (HPLC) and ultra high performance liquid chromatography (UHPLC), also known as UPLC, are analytical techniques used to separate, identify and quantitate components of complex mixtures including biological samples such as proteins and lipids as well as chemical mixtures of pesticides, drugs and oils. Both techniques are liquid chromatographic methods but differ by operating pressures (HPLC < 6000 psi < UHPLC ). Components of HPLC and UHPLC systems include columns, detectors, pumps, autosamplers and column heaters. Explore a range of UHPLC and HPLC columns for your specific sample needs including reverse phase, normal phase, ion exchange, HILIC, ion exclusion and size exclusion columns. For more specialized HPLC, explore FPLC, countercurrent LC and simulated moving bed systems. Find the best UHPLC and HPLC equipment in our peer reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Chromatography Method DevelopmentChromatography method development is the process of designing and optimizing chromatographic techniques to separate and analyze complex mixtures. This includes selecting appropriate stationary and mobile phases, determining flow rates, and optimizing detection methods. Successful method development is essential for high-quality results in fields like pharmaceuticals, food safety, and environmental analysis. Explore chromatography method development tools in our peer-reviewed product directory; compare products, check reviews, and get pricing directly from manufacturers.