nanoTherics Launches the magnefect-nano™ - The System for Improved Gene Transfection

4 Mar 2009
Samantha Rosoman
Campaign Coordinator

Product news

nanoTherics, a scientific medical research devices company founded in 2007, is pleased to announce launch of the magnefect-nano™, a new device for improved gene transfection. The system uses a unique technique applying proprietary magnet configurations and oscillating array systems to promote particle/DNA uptake into cells thus significantly improving non-viral gene transfection whilst maintaining cell viability. The system provides highly improved transfection efficiency and effectiveness - (up to 1000 x) over the best currently available cationic lipid agents at short transfection times.

nanoTherics’s primary business is supply of improved scientific devices and associated products to research laboratories in the pharmaceutical and biotechnology industries as well as academia. The Company’s products follow from >30 years combined cutting edge research into magnetic nanoparticle use conducted at Keele University and University of Florida and apply a patent-pending technology using nanoparticles and magnetic fields to facilitate enhanced delivery of biomolecules, such as DNA, into living cells. The medium to long-term opportunity for this approach relates to more effective non-viral gene therapy, an area demanding safer technology to treat genetic diseases such as cystic fibrosis.
Dr Linda Cammish, Chief Executive Officer, said, “We are delighted to be offering this new product to enable our customers to improve their transfection efficiencies with even the most hard to transfect cells”. She added, “We are committed to product development to meet our customers needs and aim to introduce a range of additional products throughout 2009. The in-vivo potential of this technology is particularly exciting, which is an area we will be placing particular focus on”.”

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Genome AnalysisGenomics, the study of genomes, includes functional genomics, evolutionary genomics and comparative genomics. There are many genomic technologies such as DNA sequencing of whole genomes, computational biology and bioinformatics. DNA and nucleic acids must be isolated and concentrated from cells for analysis with kits, automated analyzers and software. Other useful technologies for studying genomics include PCR, microarrays and electrophoresis.Cell-Based AssaysCell-based assays are used to monitor the presence, quantity and activities of a desired cellular analyte including drug molecules or biomarkers. This can reveal information on cell health (apoptosis, cytotoxicity, viability and proliferation assays), cell metabolism, cell migration and cell signaling mechanisms. Find the best cell-based assay products, kits and equipment with our peer reviewed product directory: compare products, check customer reviews and receiving pricing direct from manufacturers.High-Content ScreeningHigh-content screening (HCS), also known as high-content analysis (HCA), is a high-throughput technique used in drug discovery to identify substances that alter the phenotype of cells. HCS uses fluorescent microscopic imaging and automated image analysis to investigate cellular events such as apoptosis, cell viability, GPCR activation, oxide production, neurite outgrowth, and cell signaling. Find the best fluorescent labeling reagents, cellular assays, and high-content imaging systems in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.