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NanoLiter Dispensing for Enhanced Sensitivity

nanoLiter LLC
23 May 2012
Roger Wayman
Administrator / Office Personnel

Product news

NanoLiter LLC and iChrom announced at ASMS a sales and marketing agreement regarding nanoLiter’s technology of induction based fluidics (IBF). This includes the nanoLiter Cool Wave dispensing platform and flutronics.

The technology allows 100% of liquid samples to be dispensed into existing ESI/LC/MS systems with excellent sample introduction efficiency. The same technology can be applied to dispense liquids onto MALDI plates for enhanced high nanoLiter sensitivity as compared to microliter droplets. The essence of the technology is that it dispenses or shoots liquids as opposed to a spray where like charged droplets can repel each other and limit sample introduction efficiency.

The technology invented in a Nevada garage by a father and son team five years ago has
been placed in 42 of the most prestigious labs in the USA from the US Army at ECBC
to NIST, NIH, Amgen, Biogen Idec, U of Illinois, WI and CA. IBF can also dispense
viscous liquids like whole blood, serum, and some glues in the uL and nL volume range.

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nanoLiter LLCCompany website

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Mass SpectrometryMass spectrometry (MS) is a powerful analytical technique used to identify and quantify molecules based on the mass-to-charge ratio of gas-phase ions. It provides detailed information about the structure, composition, and properties of compounds and is widely used across fields such as environmental monitoring, materials science, drug discovery and development, food and beverage testing, and wider chemical research. Key MS techniques include tandem mass spectrometry (MS/MS), liquid chromatography–mass spectrometry (LS-MS) and inductively coupled plasma (ICP-MS). Choosing from these wide range of techniques and technologies can be a daunting task, so keep up to date with scientific applications, performance expectations, and customer reviews here all in one place. Visit our product directory to receive quotes direct from the manufacturer. MALDI-TOF MSMALDI-TOF mass spectrometers (matrix-assisted laser desorption/ionization time-of-flight) are used for the mass analysis of large molecules, including proteins, DNA, polymers and other macromolecules due to its relatively soft ionization, reducing fragmentation whilst allowing fast data acquisition. Tandem mass analyzers such as TOF/TOF systems can be used to increase resolution and sensitivity of your analysis. Find the best MALDI-TOF products in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Induction Based FluidicsASMSThe American Society for Mass Spectrometry (ASMS) is an organization dedicated to advancing the science and application of mass spectrometry. ASMS supports professionals through events, publications, and research initiatives, promoting innovation in areas like proteomics, metabolomics, and environmental analysis.

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NanoLiter Dispensing for Enhanced Sensitivity