My Lab Essentials Special: Stack the Dating Deck in Your Favor with Some Instant Chemistry

SelectScience® spoke to a scientist and entrepreneur who believes the secret to love lies in our genes

10 Feb 2016
Lois Manton-O'Byrne, PhD
Executive Editor

Editorial article

SelectScience® spoke to a scientist and entrepreneur who believes the secret to love lies in our genes

When evaluating your compatibility with a partner, you might think about aspirations in life, whether they have a good sense of humor or share any of your interests. However, in honor of Valentine’s Day, SelectScience spoke to Dr Sara Seabrooke, co-founder and Chief Science Officer at Instant Chemistry, a company that has some uncommon suggestions to test if you and your partner are meant to be.

“The Instant Chemistry test is designed to help single people find a meaningful relationship faster by not wasting time meeting people they don’t actually feel connected to,” explained Dr Seabrooke. After gaining her PhD in genetics and neuroscience, she became intrigued about the effect our genes can have on our behavior and potentially, our love life. She co-founded Instant Chemistry as a way to narrow the field if you’re single, and, if you’re already in a relationship, “to learn more about yourself and your partner and have a greater understanding of the strengths and weaknesses in your relationship.”

The Instant Chemistry test starts with a simple saliva sample. “The DNA goes through a number of processing steps before we are able to distinguish what variant of the gene someone carries” Dr Seabrooke said, and just like different gene variants can cause different eye colors, the variants of the genes Dr Seabrooke is looking for can affect our personality and are interpreted using “existing academic research”.

The genes Dr Seabrooke is interested in are focused about the histocompatibility complex, MHC/HLA, and serotonin uptake transporter, 5-HTTLPR. “Research on HLA and human relationships has been studied since its discovery back in 1995, as has the role of the serotonin uptake transport mechanism,” revealed Dr Seabrooke. “A test for HLA, measures physical chemistry; serotonin uptake is used to evaluate emotional chemistry and three other genes, DRD4, OXTR and COMT are used to measure neurocompatibility”; and a test devised by Instant Chemistry’s resident clinical psychologist forms the last part of the process, measuring psychological compatibility.

The old and the new

Once Dr Seabrooke has compared your results of the various tests to the results of your partner, a percentage is generated. We find “HLA, the serotonin update transporter and DRD4” tend to play to biggest part in compatibility, so they are weighted more strongly in the end results. In the end though, despite the high tech methodology and academic evidence for genetic compatibility testing, Instant Chemistry’s recommendation comes down to a very old adage – opposites attract!

Here are Dr Seabrooke’s lab essentials – the instruments that make Instant Chemistry possible:

Find out more information about genetic testing on our dedicated page, or learn more about Instant Chemistry.

Links

Tags

Genome AnalysisGenomics, the study of genomes, includes functional genomics, evolutionary genomics and comparative genomics. There are many genomic technologies such as DNA sequencing of whole genomes, computational biology and bioinformatics. DNA and nucleic acids must be isolated and concentrated from cells for analysis with kits, automated analyzers and software. Other useful technologies for studying genomics include PCR, microarrays and electrophoresis.PCR and Thermal CyclingPolymerase chain reaction (PCR) kits and thermal cyclers are used for the in vitro amplification of DNA permitting subsequent analysis and experimental procedures. Explore a range of high-quality polymerase, primers and nucleotides or simplify your workflow with a PCR mastermix. Find reverse transcription PCR (RT-PCR) and cDNA synthesis kits for RNA products and libraries. Quantitatively measure the amplification of DNA with real-time PCR (qPCR) and droplet digital PCR (ddPCR) kits and systems, and discover automated PCR setup solutions to increase throughput. Alternative DNA amplification methods also include recombinase polymerase amplification (RPA) kits. Find the best PCR kits and thermal cyclers and purification equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Labware and Lab SuppliesLabware and lab supplies include various forms of glassware, plasticware, reagents and personal protective equipment (PPE) and are used across all scientific laboratories, enabling daily tasks to be performed. Explore a range of flasks and beakers, petri dishes, carboys and storage bottles. Labware such as condensers, desiccators and burettes are also available for more specific tasks. Find the best labware and lab supplies in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.DNA / RNA Extraction and PurificationPurified DNA and RNA are required for numerous downstream molecular biology applications. Consequently, the importance of high-quality DNA/RNA extraction and purification equipment cannot be underestimated. Many purification kits are available and are typically optimized for nucleic acid type and source, including plasmid DNA, genomic DNA, mRNA, RNA and viral nucleic acid purification kits. Automated extraction and purification of nucleic acids can be implemented with magnetic bead separator instruments or high-throughput purification workstations. Find the best DNA/RNA extraction and purification equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.DNA SequencingDNA sequencing, such as sanger sequencing, is a biological technique that determines the precise order of nucleotide bases in a fragment or template of DNA. DNA sequencers and genetic analyzers are based on capillary electrophoresis, where labeled DNA fragments are electrophoretically separated by size as they migrate through a polymer. Find the best DNA sequencing products, including DNA sequencing kits, genomic libraries and genetic identity kits in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Gene Expression and Molecular CloningMolecular cloning is a set of techniques that utilizes vectors to transfer recombinant DNA into host cells and is an essential tool for investigating the expression of genes and proteins in bacterial or mammalian cells. A variety of vectors optimized for gene cloning and expression in a range of host organisms are available, alongside competent cells for genetic replication. Here, you can explore a range of molecular tools, high-quality genomic and cDNA libraries, premade clones, transformation and transfection reagents and mutagenesis or gene expression detection assays and expression arrays. Find the best gene expression and molecular cloning products in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Genome SequencingGenome sequencing involves determining the complete DNA sequence of an organism's genome. It provides crucial information about genetic variations, mutations, and diseases. Advances in sequencing technologies, such as next-generation sequencing (NGS), have accelerated research in genomics, diagnostics, and personalized medicine. Explore genome sequencing tools in our peer-reviewed product directory; compare products, check reviews, and get pricing directly from manufacturers.Genetic VariationReal-Time PCRReal-time PCR (RT-PCR) is a technique used to amplify and simultaneously quantify nucleic acids in real time. It is a key tool in gene expression analysis, pathogen detection, and diagnostics. RT-PCR allows for the detection of specific RNA or DNA sequences with high sensitivity and specificity. Browse our peer-reviewed product directory to find the best Real-Time PCR systems; compare products, check reviews, and get pricing directly from manufacturers.Biomarker DiscoveryClinical biomarkers refer to substances related to known medical conditions that can be accurately measured <i>in vitro</i>. Biomarkers can be used to diagnose presence of a disease and indicate disease severity. The discovery of new biomarkers is incredibly valuable in the field of diagnostics.
My Lab Essentials Special: Stack the Dating Deck in Your Favor with Some Instant Chemistry