More applications. More answers.

5 Apr 2009
Samantha Rosoman
Campaign Coordinator

Product news

We continue to help drive your cancer research forward with the introduction of new products and applications.

For the latest in cancer research products and solutions, come to booth 2242 at AACR and learn about our solutions in the areas of genetic analysis, functional analysis, gene expression, and protein biomarker research:

* In-booth poster presentations
* New product announcements
* Current promotions

In-Booth Poster Presentation Schedule

Next Generation Sequencing with the SOLiD™ 3 System
Sunday, April 19, 1:00-1:45 p.m.
Monday, April 20, 3:00-3:45 p.m.

* Large-scale SNP detection via ligation-based dibase sequencing across multiple HapMap individuals: NA18507, NA19240, and NA12878
* Resolving structural variations using SOLiD™ mate pair sequencing technology
* SOLiD™ sequencing of whole-genome bisulfite-converted libraries prepared from nanogram quantities
* The utility of capillary electrophoresis and next generation sequencing platforms for scientific discovery

New High-Throughput Genotyping Solutions
Sunday, April 19, 3:00-3:45 p.m.
Tuesday, April 21, 10:00-10:45 a.m.

* Development of TaqMan® DME genotyping assays on TaqMan® low-density arrays
* A breakthrough system for nanowell high-throughput genotyping
* Fast TaqMan® genotyping workflow for a wide variety of plant and animal samples
* Fast TaqMan® genotyping workflow for non-invasive biological samples


Tools for Molecular Biology Research: From RNA to Protein and Everything in Between
Monday, April 20, 10:00-10:45 a.m.
Tuesday, April 21, 1:00-1:45 p.m.

* Development of TaqMan® copy number assays for copy number analysis
* Relative peptide quantitation in time course experiments using Scheduled MRM™ methods
* High-performance Fast SYBR® Green Master Mix for rapid real-time PCR*
* Enhanced workflow for sequencing PCR products by capillary electrophoresis
* Automate Cells-to-CT™ kits for high-throughput expression analysis†


Big Advances in Small RNA Research
Monday, April 20, 10:00-10:45 a.m.
Tuesday, April 21, 3:00-3:45 p.m.

* Single-cell microRNA and mRNA profiling reveals unique gene expression signatures and heterogeneities in mouse ES cells†
* Multiplexed TaqMan® based MicroRNA expression profiling of cancer and stem cells MicroRNA variation in cancerous hepatocytes compared to normal hepatocytes
* Next-generation siRNAs: Combining support vector machine learning with novel chemical modifications for more consistent siRNA performance in high-content screens*
* An expression atlas of small RNAs generated using the SOLiD™ sequencing system

* Monday only.
† Tuesday only.

TaqMan Gene Expression Assays

Thermo Fisher Scientific

TaqMan® Gene Expression Assays are a comprehensive collection of over 1,000,000 probe and primer sets for quantitative gene expression analysis of 13 species including human, mouse, rat, Arabidopsis, Drosophila, and C. elegans genes. These assays let you quickly, easily, and affordably perform precise gene expression studies using real-time PCR. TaqMan®-based assays provide unmatched sensitivity, specificity, and reproducibility enabling data comparisons across experiments and labs. Ordering is easy. Simply search for the gene or transcript of interest using a number of public identifiers, and place the relevant assays in your basket. Reduce target discovery and validation time. Our validated bioinformatics design pipeline provides you with multiple pre-designed assays for each transcript. Universal cycling conditions eliminates the need to optimize conditions individually and enables any combination of assays to be run together. Assays are delivered in a single tube format. Just add TaqMan® Master Mix and your cDNA sample to generate accurate, reproducible, and truly quantitative gene expression data. Analyze on any Applied Biosystems Real-Time PCR System.

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TaqMan SNP Genotyping Assays

Thermo Fisher Scientific

With over 4.5 million SNP assays available, including 3.5 million HapMap SNPs, 70K cSNPs, and 160,000 validated assays, Applied Biosystems SNP Genotyping Assays make it easy to perform SNP genotyping studies with the precision of TaqMan® reagent-based chemistry. These assays provide SNP detection capabilities with high-confidence results. The large selection of SNP assays helps advance your screening, association, candidate region, candidate gene, or fine-mapping studies. Easy-to-use, single tube format. Robust assay design provides highly accurate, reproducible and reliable results. Easy assay ordering and a simple workflow provides quick results. Choose from Human or Mouse pre-designed SNP Assays. All TaqMan® SNP Genotyping Assays are provided in a ready-to-use, single-tube format for the simplest genotyping workflow available and immediate results. Designed for use on all Applied Biosystems Real-Time PCR Systems and the TaqMan® OpenArray™ Genotyping System.

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Links

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Genome AnalysisGenomics, the study of genomes, includes functional genomics, evolutionary genomics and comparative genomics. There are many genomic technologies such as DNA sequencing of whole genomes, computational biology and bioinformatics. DNA and nucleic acids must be isolated and concentrated from cells for analysis with kits, automated analyzers and software. Other useful technologies for studying genomics include PCR, microarrays and electrophoresis.Cell-Based AssaysCell-based assays are used to monitor the presence, quantity and activities of a desired cellular analyte including drug molecules or biomarkers. This can reveal information on cell health (apoptosis, cytotoxicity, viability and proliferation assays), cell metabolism, cell migration and cell signaling mechanisms. Find the best cell-based assay products, kits and equipment with our peer reviewed product directory: compare products, check customer reviews and receiving pricing direct from manufacturers.DNA / RNA Extraction and PurificationPurified DNA and RNA are required for numerous downstream molecular biology applications. Consequently, the importance of high-quality DNA/RNA extraction and purification equipment cannot be underestimated. Many purification kits are available and are typically optimized for nucleic acid type and source, including plasmid DNA, genomic DNA, mRNA, RNA and viral nucleic acid purification kits. Automated extraction and purification of nucleic acids can be implemented with magnetic bead separator instruments or high-throughput purification workstations. Find the best DNA/RNA extraction and purification equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Protein PurificationProtein purification is a vital step in drug discovery, therapeutics, biotech and life science research. The purification process typically involves subcellular or membrane protein extraction with cell lysis kits, separation of proteins from cell debris by filtration or spin columns, and the isolation of proteins of interest from other proteins and impurities with affinity purification (including fusion protein tags and antibody binding proteins A, G and L), immunoprecipitation or chromatographic methods, such as ion exchange, size exclusion and immobilized metal affinity chromatography. All purification methods come in multiple formats for your laboratory needs, including agarose or magnetic beads, resins, columns and filter plates. Find the best protein purification equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Clinical GeneticsMolecular Genetics covers the analysis of hereditary genetic disease and chromosomal abnormalities. Genetics can be analysed using DNA, RNA, and protein microarrays, PCR, RT PCR and DNA sequencing. Genetic equipment includes genetic workstations, thermal cyclers, cooling blocks and electrophoresis products. Diagnostic kits are used for DNA / RNA extraction and purification.