Molecular Devices Launches High-Content Screening System: ImageXpress Micro XL

12 Sept 2011

Product news

Molecular Devices LLC., today announced the launch of the XL model, part of the ImageXpress® Micro System. The ImageXpress Micro XL System offers researchers the benefit of imaging twice the sample area to deliver statistically relevant results in half the time - an additional benefit to the existing ImageXpress Micro Widefield High-Content Screening System.

Incorporating state-of-the-art detector and illumination technologies, the system can capture cellular resolution images using a single-field that encompasses one 384 well, maximizing content up to 2-fold of what is acquired with standard camera HCS systems. This generous increase in field-of-view allows users to image twice the number of objects per image, minimizing the need to tile when capturing sizeable objects that span across the sample. The new MetaXpress® 4 Software complements the ImageXpress Micro XL System by increasing image analysis speed 100%, allowing acquisition and analysis of greater than 10 million cells per hour.

The ImageXpress Micro XL System is designed to be a flexible widefield high content screening system maintaining an extensive sample and objective compatibility. Combined with the longevity of a 10,000+ hour light source, researchers can feel confident in system robustness, while gaining a greater peace-of-mind the instrument will grow with their expanding applications.

“The launch of the ImageXpress Micro XL System is a shining example of Molecular Devices’ ability to support researchers’ efforts to run more screens and perform hit selection faster. Whether you are searching for rare events or investigating multifaceted cell signaling pathways, we are excited to offer twice the data points per image to decrease your time to perform cellular- and high-resolution screens” said Jennifer McKie, Senior Marketing Director, BioImaging at Molecular Devices.

“Assay window and reliability are enhanced with 3-log dynamic range and <5% CV for intensities across the plate, making certain your scientific breakthroughs are picture perfect for research publications” stated Jennifer McKie. “We believe these enhancements ensure researchers are equipped with the latest high content imaging technology to be at the forefront of drug discovery and cellular research.”

The ImageXpress Micro XL System will be showcased at the MipTec, September 20 – 22 2011, Basel, Switzerland (Booth D33). For more information regarding the ImageXpress Micro XL System, go to the company article page on the right.

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High-Throughput ScreeningHigh-throughput screening (HTS) is an automated drug discovery technique for identification of active compounds against a compound library. Use HTS readers and integrated assay preparation / analysis workstations to screen your compounds. Identify active compounds against various HTS libraries, including membranes, proteins and peptides and HTS cell lines. Find the best high-throughput screening products in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.High-Content ScreeningHigh-content screening (HCS), also known as high-content analysis (HCA), is a high-throughput technique used in drug discovery to identify substances that alter the phenotype of cells. HCS uses fluorescent microscopic imaging and automated image analysis to investigate cellular events such as apoptosis, cell viability, GPCR activation, oxide production, neurite outgrowth, and cell signaling. Find the best fluorescent labeling reagents, cellular assays, and high-content imaging systems in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.
Molecular Devices Launches High-Content Screening System: ImageXpress Micro XL