Molecular Devices Announces Development of a Novel Platform Combining a Plate Reader with an Imaging Cytometer

15 Jan 2013

Product news

Molecular Devices announced today it has developed an addition to the SpectraMax® product line. The new multi-mode microplate platform will have an imaging cytometer option, adding rich cellular resolution assays and visualization to well-based intensity readings. The new system will make cytometry more accessible to a wider audience, providing researchers with cellular analysis capability without the need for investment in complex imaging systems. With the ability to inspect both bright-field and fluorescent images, it will provide insight into phenotypic changes that are important for understanding cytotoxicity, cell proliferation, and protein expression.

The imaging cytometer option will provide rapid access to vital cell-based data without the complexity that is typical of automated microscopy and flow cytometry. The enhanced SoftMax® Pro Microplate Data Acquisition and Analysis Software will provide the user interface and lend step-by-step guidance, from initial setup of image acquisitions to comprehensive data analysis.

“This new platform is exemplary of our commitment to providing a flexible instrument that is capable of performing many different types of assays,” said Chris Kier, Ph.D, Molecular Devices Director of Product Management, Bioimaging. “The new imaging cytometer option will allow researchers to collapse their workflow by keeping their cell-based research within the lab and on the same instrument when requiring both cellular resolution assays and standard plate assays.”

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High-Throughput ScreeningHigh-throughput screening (HTS) is an automated drug discovery technique for identification of active compounds against a compound library. Use HTS readers and integrated assay preparation / analysis workstations to screen your compounds. Identify active compounds against various HTS libraries, including membranes, proteins and peptides and HTS cell lines. Find the best high-throughput screening products in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Microplate Readers / DetectorsMicroplate readers are used to automate the detection and analysis of labeled or label-free components in microplates during assays or live-cell monitoring. Microplate readers are generally distinguished by their mode of detection. Types include absorbance, luminescence, fluorescence intensity, fluorescence polarization, TRF / FRET and multimode microplate readers. Microplate readers deliver a high throughput of samples by reading multiple wells simultaneously, with the 96-well format the most commonly used. As a result, microplate readers are often used in the drug discovery, bioassays, research and pharmaceutical industries for screening applications. Microplate loading can also be automated, with robotic microplate stackers to increase throughput. Find the best microplate readers in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Flow Cytometry / Cell CountingFlow cytometers are used to count, sort and examine multiple characteristics of cells. Other cell analysis equipment includes image cytometers, cell counters, fluorescence-activated cell sorters (FACS), magnetic-activated cell sorters (MACS), and a range of flow cytometry assay kits. Flow cytometers can reveal information on cell viability, cell proliferation, apoptosis and cell cycle progression, as well as identify cell populations and intracellular or cell-surface molecules. Additionally, some flow cytometers, known as FACS, have an additional sorting function after analysis. Cell counters and image cytometers count live and dead cell populations and can also conduct cell proliferation assays. Find the best flow cytometers, cell counters and cell sorters in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.SLASThe Society for Laboratory Automation and Screening (SLAS) is an organization focused on laboratory automation, high-throughput screening, and biotechnology innovation. SLAS promotes scientific advancements through conferences, publications, and industry collaborations. CytotoxicityCytotoxicity assays measure the toxic effects of substances on cells, often used in drug testing and environmental studies. These tests are crucial in determining the safety of chemicals and pharmaceutical compounds. Explore cytotoxicity testing tools in our peer-reviewed product directory; compare products, check reviews, and get pricing directly from manufacturers.CytometryCytometry is a broad term for the quantitative analysis of cells and cell systems. The most popular methods to study cytometry are flow cytometry and image cytometry.ImagingImaging techniques are essential for obtaining visual representations of samples to understand structures, processes, and function in biological, chemical, and physical research. These tools range from traditional light microscopy to advanced imaging modalities like MRI and electron microscopy, providing researchers with valuable data for diagnostics, drug discovery, and material analysis. Explore imaging solutions in our peer-reviewed product directory to compare products, check reviews, and get pricing directly from manufacturers.Data AcquisitionData acquisition refers to the collection and organization of information and data sets.
Molecular Devices Announces Development of a Novel Platform Combining a Plate Reader with an Imaging Cytometer