SelectScience
Join Free
Accelerating Science
NewsDrug Discovery & Development

MOBILion Systems presents plans for its next-generation proteomics platform at ASMS 2025

MOBILion Systems

MOBILion Systems to highlight customer use cases from its MOBIE Platform

3 Jun 2025

Product news

MOBILion Systems will exhibit at the 73rd Annual American Society for Mass Spectrometry (ASMS) Conference in Baltimore, MD from June 1–5. It will highlight the transformative impact its MOBIE® High-Resolution Ion Mobility product is having across a wide range of applications and showcase early performance of its next-generation proteomics system, BILLIE™.

More than 50 abstracts including oral and poster presentations will demonstrate how independent researchers across pharmaceutical development, chiral molecule analysis, lipidomics and PFAS research are driving innovation with the MOBIE system. These real-world applications reflect growing market adoption and the expanding impact of MOBILion’s existing MOBIE product across critical and emerging workflows.

Alongside its commercial platform, MOBILion will present the latest data and collaborator results powered by its most recent advancement: Parallel Accumulation Mobility Aligned Fragmentation (PAMAF). This novel mode of operation is the foundation for the forthcoming BILLIE platform, enabling increased speed, sensitivity, and selectivity for LC-HRMS-based proteomics.

PAMAF is designed to address the long-standing limitations of traditional tandem quadrupole mass spectrometry by replacing the slow and lossy quadrupole isolation step with high-resolution ion mobility separation. This allows BILLIE to deliver MS/MS fragmentation at over 500 Hz and utilize nearly 100% of available ions, resulting in faster data acquisition, greater signal sensitivity, and improved quantitative accuracy in even the most challenging biological samples.

“ASMS is the ideal venue to highlight the exciting breakthroughs our users are achieving with the MOBIE system, and to share where we are heading with BILLIE,” said Dr. Melissa Sherman, CEO of MOBILion Systems.

Dr. Daniel DeBord, Chief Technology Officer at MOBILion, added, “For over two decades, scientists have worked to overcome the speed and sensitivity limitations of traditional MS workflows. PAMAF enables fragmentation data with dramatically higher signal-to-noise at speeds up to five times faster than conventional systems. We’re excited to showcase this next frontier in proteomics at ASMS.”

Want the latest science news straight to your inbox? Become a SelectScience member for free today>>

Links

MOBILion SystemsCompany website

Tags

Mass SpectrometryMass spectrometry (MS) is a powerful analytical technique used to identify and quantify molecules based on the mass-to-charge ratio of gas-phase ions. It provides detailed information about the structure, composition, and properties of compounds and is widely used across fields such as environmental monitoring, materials science, drug discovery and development, food and beverage testing, and wider chemical research. Key MS techniques include tandem mass spectrometry (MS/MS), liquid chromatography–mass spectrometry (LS-MS) and inductively coupled plasma (ICP-MS). Choosing from these wide range of techniques and technologies can be a daunting task, so keep up to date with scientific applications, performance expectations, and customer reviews here all in one place. Visit our product directory to receive quotes direct from the manufacturer. ProteomicsProteomics is the systemic bioinformatics study of proteins and amino acids, including their structure, size, function and identification. Tools used in proteomics include chromatography, blotting and gels, protein arrays, mass spectrometry and ELISA and associated analysis software. Analyzers and proteomic systems should be sensitive, high resolution, fast and may be automated for high-throughput.LC-MSLC-MS (liquid chromatography-mass spectrometry) systems and equipment are used for separation and quantitative analysis of complex mixtures, combining liquid chromatography and mass spectrometry. Quantify proteins, contaminants, pesticides or screen for drug metabolites with a high level of sensitivity. LC-MS systems and equipment include reverse phase, normal phase and specialized columns integrated with various MS detectors such as time-of-flight (TOF), quadrupole, orbitrap or ion trap mass analyzers. LC-MS/MS instruments equipped with a qTOF or triple quadrupole analyzer give greater sensitivity and resolving power to your analysis. Find the best LC-MS equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.ASMSThe American Society for Mass Spectrometry (ASMS) is an organization dedicated to advancing the science and application of mass spectrometry. ASMS supports professionals through events, publications, and research initiatives, promoting innovation in areas like proteomics, metabolomics, and environmental analysis.

Related articles